Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.68 |
| ▸ | CA2 | P00918 | 6/20 | 0.68 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.68 |
| ▸ | PARP1 | P09874 | 1/20 | 0.68 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.68 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.68 |
| ▸ | CES2 | O00748 | 2/20 | 0.67 |
| ▸ | CES1 | P23141 | 2/20 | 0.67 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953009 | 0.88 | CA1 (0.65) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL18687125 | 0.88 | CA1 (0.65) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL272999 | 0.81 | CA1 (0.57) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL41284 | 0.81 | CA1 (0.68) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL201761 | 0.81 | PARP10 (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL9418310 | 0.80 | RXFP1 (0.79) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL557152 | 0.80 | CES2 (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL51509 | 0.80 | RXFP1 (0.79) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL14507040 | 0.80 | CES2 (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL30420427 | 0.80 | CA1 (0.55) | CA1CA2PARP10PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119377-B1 | PHOTOPOLYMERISABLE AND DUAL HARDENING DENTAL MATERIAL BASED ON THIOUREA DERIVATIVES AND BISACYLDIALKYLGERMANIUM-COMPOUNDS | IVOCLAR VIVADENT AG (LI) | 2021-12-29 | — | — | EP | claimed |
| CN-106132380-B | Photopolymerizable dual-cure dental materials based on thiourea derivatives | 义获嘉伟瓦登特公司 | 2020-02-11 | — | — | CN | claimed |
| EP-2921156-B1 | Monomer mixture for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2019-10-02 | — | — | EP | claimed |
| US-10195121-B2 | Photopolymerizable and dual-curing dental materials based on thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2019-02-05 | — | — | US | claimed |
| US-10130562-B2 | Monomer mixture for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2018-11-20 | — | — | US | claimed |
| US-20170143592-A1 | MONOMER MIXTURE FOR THE PREPARATION OF DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2017-05-25 | — | — | US | claimed |
| US-20170128328-A1 | Photopolymerizable and dual-curing dental materials based on thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2017-05-11 | — | — | US | claimed |
| EP-2921154-B1 | Photopolymerisable and dual hardening dental material based on thiourea derivatives and bisacyldialkylgermanium-compounds | IVOCLAR VIVADENT AG (LI) | 2017-03-08 | — | — | EP | claimed |
| EP-3119377-A1 | PHOTOPOLYMERISABLE AND DUAL CURING DENTAL MATERIALS BASED ON THIOUREA DERIVATIVES | Ivoclar Vivadent AG (LI) | 2017-01-25 | — | — | EP | claimed |
| WO-2015140276-A1 | PHOTOPOLYMERISABLE AND DUAL CURING DENTAL MATERIALS BASED ON THIOUREA DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2015-09-24 | — | — | WO | claimed |
| WO-2015139811-A1 | MONOMER MIXTURES FOR PRODUCING DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2015-09-24 | — | — | WO | claimed |
| EP-2921154-A1 | Photopolymerisable and dual hardening dental material based on thiourea derivatives and bisacyldialkylgermanium-compounds | Ivoclar Vivadent AG (LI) | 2015-09-23 | — | — | EP | claimed |
| EP-2921156-A1 | Monomer mixture for the preparation of dental materials | Ivoclar Vivadent AG (LI) | 2015-09-23 | — | — | EP | claimed |
| US-20260060900-A1 | DENTAL COMPOSITE RESIN KIT | SHOFU INC. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-3542775-B1 | COMPOSITION WITH EXCELLENT STORAGE STABILITY USING HIGHLY BASIC FILLER | SHOFU INC (JP) | 2025-04-02 | — | — | EP | disclosed |
| WO-2025058006-A1 | PHOTOCURABLE ADHESIVE COMPOSITION, BONDED BODY, AND 2-CYANOACRYLATE COMPOSITION FOR PHOTOCURABLE ADHESIVE | 東亞合成株式会社 | 2025-03-20 | — | — | WO | disclosed |
| WO-2015139811-A1 | MONOMER MIXTURES FOR PRODUCING DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2015-09-24 | — | — | WO | disclosed |
| EP-2921154-A1 | Photopolymerisable and dual hardening dental material based on thiourea derivatives and bisacyldialkylgermanium-compounds | Ivoclar Vivadent AG (LI) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921156-A1 | Monomer mixture for the preparation of dental materials | Ivoclar Vivadent AG (LI) | 2015-09-23 | — | — | EP | disclosed |
| US-20080076847-A1 | Polymerizable compositions with acylgermanes as initiatiors | IVOCLAR VIVADENT AG (LI) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060900-A1 | DENTAL COMPOSITE RESIN KIT | BOLA2; BOLA2B, LBR, COL2A1 | CA1 1024/4885CA2 959/4885PARP10 1943/4885 |
| US-20080076847-A1 | Polymerizable compositions with acylgermanes as initiatiors | NR1I3, NR4A1, NR1I2 | CA1 2753/4885CA2 3675/4885PARP10 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.