Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.68 |
| ▸ | CA2 | P00918 | 6/20 | 0.68 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.68 |
| ▸ | PARP1 | P09874 | 1/20 | 0.68 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.68 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.68 |
| ▸ | CES2 | O00748 | 2/20 | 0.67 |
| ▸ | CES1 | P23141 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201761 | 0.81 | PARP10 (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL4954760 | 0.81 | CA1 (0.68) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL2419348 | 0.80 | MAPT (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL11586276 | 0.80 | PARP10 (0.65) | PARP10PARP2PARP4MAPTRAB9A | |
| SCHEMBL51509 | 0.80 | RXFP1 (0.79) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL14507040 | 0.80 | CES2 (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL9418310 | 0.80 | RXFP1 (0.79) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL557152 | 0.80 | CES2 (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL4953009 | 0.79 | CA1 (0.65) | CA1CA2PARP10PARP1PARP2 | |
| Hydrochloric Acid SCHEMBL408766 | 0.79 | PARP10 (0.95) | CA1CA2PARP10PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1796 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| CN-114805068-B | Preparation method of chiral alpha-hydroxy-beta-keto ester compound | 南京工业大学 | 2023-07-21 | — | — | CN | claimed |
| CN-116239647-A | Benzimidazole alkyl bromide-timosaponin derivative and preparation method and application thereof | 云南大学 | 2023-06-09 | — | — | CN | claimed |
| US-11235330-B2 | Hydrogel membrane and methods for selective retrieval of microbial targets | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-02-01 | — | — | US | claimed |
| EP-3172213-B1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-09-22 | — | — | EP | claimed |
| US-20200330984-A1 | HYDROGEL MEMBRANE AND METHODS FOR SELECTIVE RETRIEVAL OF MICROBIAL TARGETS | NATIONAL SCIENCE FOUNDATION | 2020-10-22 | — | — | US | claimed |
| EP-2955575-B1 | RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, AND POLYPHENOL DERIVATIVE USED IN SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2020-07-29 | — | — | EP | claimed |
| CN-108299401-B | 3-benzyl substituted coumarin-imidazole salt compound and preparation method thereof | 红河学院 | 2020-06-30 | — | — | CN | claimed |
| CN-109053847-B | 17 β -imidazolidinyl bromide-dehydroepiandrostane derivative and preparation method and application thereof | 云南大学 | 2020-05-19 | — | — | CN | claimed |
| CN-110123809-A | 5- methyl-dihydro benzofuran-application of the imidazole salt compound in pharmacy | 中国科学院昆明植物研究所 | 2019-08-16 | — | — | CN | claimed |
| WO-1994003489-A1 | ANTI-INFLAMMATORY PEPTIDE ANALOGS AND TREATMENT TO INHIBIT VASCULAR LEAKAGE IN INJURED TISSUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-02-17 | — | — | WO | claimed |
| EP-0071682-B1 | NEW ANTHRANILIC ACID ESTERS HAVING ANTI-INFLAMMATORY ACTIVITY AND THEIR PREPARATION | Council of Scientific and Industrial Research (IN) | 1985-11-13 | — | — | EP | claimed |
| US-4456755-A | ANTIBIOTICS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1984-06-26 | — | — | US | claimed |
| US-4361514-A | Carbon analogs of penicillin | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1982-11-30 | — | — | US | claimed |
| US-4282149-A | Carbon and oxygen analogs of penicillin | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1981-08-04 | — | — | US | claimed |
| US-4137322-A | ML-236B carboxylic acid derivatives and their use as antihyperlipemic agents | SANKYO COMPANY LIMITED (JP) | 1979-01-30 | — | — | US | claimed |
| US-4075340-A | ANTIINFLAMMATORY, ANTIARRYTHMIC, ANTICOAGULANTS | PARCOR (FR) | 1978-02-21 | — | — | US | claimed |
| US-4071681-A | Process for preparing beta-lactam antibiotic substances | SANKYO COMPANY LIMITED (JA) | 1978-01-31 | — | — | US | claimed |
| US-4031215-A | STREPTOMYCES, ALDOL CONDENSATION | KAKEN CHEMICAL CO., LTD. (JA) | 1977-06-21 | — | — | US | claimed |
| US-4016155-A | Process for preparing cephalosporin derivatives | SANKYO COMPANY LIMITED (JA) | 1977-04-05 | — | — | US | claimed |