Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | SDCBP | O00560 | 1/20 | 0.39 |
| ▸ | SDC2 | P34741 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 2/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953176 | 0.88 | PTGS2 (0.50) | CA2CA9CA12ACLYCA1 | |
| SCHEMBL4953413 | 0.84 | PTGS2 (0.48) | CA2CA9ACLYKDM1APTGS2 | |
| SCHEMBL4946259 | 0.81 | ACLY (0.45) | ACLY | |
| SCHEMBL4950128 | 0.79 | GRIA2 (0.52) | KDM1A | |
| SCHEMBL4951076 | 0.76 | PTGS2 (0.36) | ACLYPTGS2 | |
| SCHEMBL14124478 | 0.75 | GRIA4 (0.48) | ACLYPTGS1PTGS2 | |
| SCHEMBL5141157 | 0.74 | PTGS2 (0.37) | CA2CA9ACLYKDM1APTGS1 | |
| SCHEMBL4953693 | 0.74 | GRIA4 (0.49) | CA2CA9CA12ACLYCA1 | |
| SCHEMBL4951303 | 0.74 | GRIA2 (0.49) | CA2CA9CA12ACLYCA1 | |
| SCHEMBL4948474 | 0.73 | RORC (0.39) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |