Butyric Acid

Butyric Acid

SCHEMBL4955048

C=CCC1CCCCC1.CCCC(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
LMNA P02545 1/20 0.41
ALDH1A1 P00352 2/20 0.36
KDM5A P29375 3/20 0.35
PHF8 Q9UPP1 3/20 0.35
KDM2A Q9Y2K7 3/20 0.35
KDM4C Q9H3R0 2/20 0.35
KDM4A O75164 1/20 0.35
CYP1A2 P05177 1/20 0.34
CASP1 P29466 1/20 0.34
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
TBXA2R P21731 1/20 0.33
MAPT P10636 1/20 0.33
HSD11B1 P28845 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL203063 0.89 FFAR3 (0.40) FFAR3LMNAALDH1A1CYP1A2CASP1
Acetic Acid SCHEMBL1471719 0.83 EPHX2 (0.36) LMNAALDH1A1NOS3NOS1NOS2
Bicarbonate SCHEMBL5712008 0.83 EPHX2 (0.38) LMNANOS3NOS1NOS2
Butyric Acid SCHEMBL5073946 0.83 FFAR3 (0.45) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL5073945 0.83 FFAR3 (0.45) FFAR3HDAC3HDAC1HDAC2HDAC8
Acrylic Acid SCHEMBL28095949 0.80 LMNA (0.42) LMNANOS3NOS1NOS2
Butyric Acid SCHEMBL5061211 0.78 FFAR3 (0.52) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL7063115 0.77 NOS1 (0.42) ALDH1A1CYP1A2NOS3NOS1NOS2
SCHEMBL2499186 0.77 NOS1 (0.42) ALDH1A1CYP1A2NOS3NOS1NOS2
SCHEMBL2500447 0.77 NOS1 (0.42) ALDH1A1CYP1A2NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101760317-A Pineapple flavor essence XINGUANG LIU 2010-06-30 CN claimed
US-20030036489-A1 Consumable composition comprising perfumed particles and article containing the same THE PROCTER & GAMBLE COMPANY 2003-02-20 US claimed
WO-2002090479-A1 PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
CN-106929370-A Alcoholic beverage emulsification flavor compositions 高砂香料工业株式会社 2017-07-07 CN disclosed
CN-103189076-A Deodorant composition for sulfides TAKASAGO PERFUMERY CO LTD 2013-07-03 CN disclosed
CN-101405034-B Liquid deodorant composition and method of deodorization TAKASAGO PERFUMERY CO LTD 2013-03-20 CN disclosed
CN-101760317-A Pineapple flavor essence XINGUANG LIU 2010-06-30 CN disclosed
CN-1874693-B Food products containing a fruit component TAKASAGO PERFUMERY CO LTD 2010-05-05 CN disclosed
CN-101405034-A Liquid deodorant composition and method of deodorization TAKASAGO PERFUMERY CO LTD (JP) 2009-04-08 CN disclosed
US-20080221003-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-09-11 US disclosed
US-20080207476-A1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCE PROPERTIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-28 US disclosed
EP-1383858-A1 DRYER-ADDED FABRIC SOFTENING ARTICLES AND METHODS The Procter & Gamble Company (US) 2004-01-28 EP disclosed
US-20030036489-A1 Consumable composition comprising perfumed particles and article containing the same THE PROCTER & GAMBLE COMPANY 2003-02-20 US disclosed
US-20030024997-A1 Air freshening compositions, articles comprising same and methods THE PROCTER & GAMBLE COMPANY 2003-02-06 US disclosed
US-20030013632-A1 Dryer-added fabric softening articles and methods THE PROCTER & GAMBLE COMPANY 2003-01-16 US disclosed
WO-2002089862-A2 AIR FRESHENING COMPOSITIONS, ARTICLES COMPRISING SAME AND METHODS FOR PREPARING SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed
WO-2002090480-A1 DRYER-ADDED FABRIC SOFTENING ARTICLES AND METHODS THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed
WO-2002090479-A1 PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030024997-A1 Air freshening compositions, articles comprising same and methods PIEZO1, TMEM63A, KIT FFAR3 1139/4885HDAC3 3540/4885HDAC1 2130/4885
US-20080207476-A1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCE PROPERTIES DSC1, DSG1, PIEZO1 FFAR3 2735/4885HDAC3 903/4885HDAC1 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.