Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 6/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955197 | 0.91 | PGR (0.33) | ESR1PGRERN1ALDH1A1MEN1 | |
| SCHEMBL4954496 | 0.89 | PGR (0.36) | ESR1PGRMEN1KMT2A | |
| SCHEMBL4954623 | 0.87 | ESR1 (0.33) | ESR1PGRERN1ALDH1A1MEN1 | |
| SCHEMBL3973937 | 0.87 | ESR1 (0.40) | ESR1PGRALDH1A1MEN1KMT2A | |
| SCHEMBL211920 | 0.83 | ERN1 (0.39) | ESR1PGRERN1ALDH1A1MEN1 | |
| SCHEMBL4949774 | 0.81 | PGR (0.32) | ESR1PGRMEN1KMT2APOLB | |
| SCHEMBL4585337 | 0.81 | ALDH1A1 (0.40) | ESR1PGRALDH1A1MEN1KMT2A | |
| SCHEMBL4954700 | 0.80 | PTGS1 (0.33) | ESR1PGRERN1ALDH1A1MEN1 | |
| SCHEMBL4955183 | 0.80 | ERN1 (0.33) | ESR1PGRERN1ALDH1A1MEN1 | |
| SCHEMBL12936012 | 0.75 | ERN1 (0.44) | ERN1MEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456323-B2 | 1,3-bis(3-formyl-4-hydroxyphenyl)adamantanes and polynuclear polyphenols derived therefrom | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-11-25 | — | — | US | disclosed |
| US-20080242896-A1 | 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242896-A1 | 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom | HNMT, NEFM, CD69 | ESR1 2358/4885PGR 2798/4885ERN1 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.