SCHEMBL3973937

SCHEMBL3973937

CCc1cc(C23CC4CC(C2)CC(c2cc(CC)c(O)c(CC)c2)(C4)C3)cc(CC)c1O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.40
PGR P06401 6/20 0.40
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4585337 0.90 ALDH1A1 (0.40) ESR1PGRALDH1A1LMNAMEN1
SCHEMBL4955291 0.87 ESR1 (0.35) ESR1PGRALDH1A1LMNAMEN1
SCHEMBL3974495 0.83 MEN1 (0.53) ESR1PGRALDH1A1LMNAMEN1
SCHEMBL18009641 0.81 GRIN2D (0.47) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL12897748 0.81 MEN1 (0.42) ALDH1A1LMNAMEN1KMT2APOLB
SCHEMBL4955968 0.80 PGR (0.33) ESR1PGRMEN1KMT2APOLB
SCHEMBL209155 0.78 SHBG (0.42) ESR1PGRALDH1A1LMNAMEN1
SCHEMBL4955197 0.78 PGR (0.33) ESR1PGRALDH1A1LMNAMEN1
SCHEMBL2048427 0.77 ACHE (0.43) ESR1PGRALDH1A1LMNAMEN1
SCHEMBL4956281 0.77 MEN1 (0.33) ESR1PGRLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed