Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.50 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420660 | 0.98 | CYP4Z1 (0.54) | CYP4Z1CYP4F2CYP4A11ALOX5CYP4F11 | |
| Hydrochloric Acid SCHEMBL7420658 | 0.97 | CYP4Z1 (0.53) | CYP4Z1CYP4F2CYP4A11ALOX5CYP4F11 | |
| SCHEMBL27469498 | 0.95 | ALOX5 (0.56) | CYP4Z1CYP4F2CYP4A11ALOX5CYP4F11 | |
| SCHEMBL2412884 | 0.88 | CYP4F2 (0.67) | CYP4Z1CYP4F2CYP4A11ALOX5NAMPT | |
| SCHEMBL9671800 | 0.86 | CYP4Z1 (0.65) | CYP4Z1CYP4F2CYP4A11ALOX5CYP4F11 | |
| SCHEMBL9554159 | 0.84 | LTA4H (0.51) | CYP4Z1CYP4F2CYP4A11ALOX5CYP4F11 | |
| SCHEMBL6328999 | 0.83 | ALOX5 (0.69) | CYP4Z1CYP4F2CYP4A11ALOX5CYP4F11 | |
| SCHEMBL14570534 | 0.83 | CYP4Z1 (0.62) | CYP4Z1CYP4F2CYP4A11ALOX5CYP4F11 | |
| SCHEMBL6204525 | 0.82 | CYP4Z1 (0.60) | CYP4Z1CYP4F2CYP4A11ALOX5CYP4F11 | |
| SCHEMBL5542104 | 0.82 | CYP4Z1 (0.60) | CYP4Z1CYP4F2CYP4A11ALOX5CYP4F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085273-A1 | VEHICLE FOR THE TRANSPORT OF A CHOSEN MOLECULE TO A CELL | SYNVOLUX IP B.V. (NL) | 2008-04-10 | — | — | US | disclosed |
| US-20080085273-A1 | VEHICLE FOR THE TRANSPORT OF A CHOSEN MOLECULE TO A CELL | SYNVOLUX IP B.V. (NL) | 2008-04-10 | — | — | US | disclosed |
| US-20080085273-A1 | VEHICLE FOR THE TRANSPORT OF A CHOSEN MOLECULE TO A CELL | SYNVOLUX IP B.V. (NL) | 2008-04-10 | — | — | US | disclosed |
| US-7339065-B2 | Design and synthesis of optimized ligands for PPAR | BETHESDA PHARMACEUTICALS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-20070099969-A1 | Design and synthesis of optimized ligands for ppar | THE UNIVERSITY OF MISSISSIPPI | 2007-05-03 | — | — | US | disclosed |
| US-7115623-B2 | PDE IV inhibitors | ASKA PHARMACEUTICALS CO., LTD. (JP) | 2006-10-03 | — | — | US | disclosed |
| CN-1224624-C | 1, 8-naphthyridin-2 (1H) -one derivatives | GRELAN PHARMACEUTICAL CO (JP) | 2005-10-26 | — | — | CN | disclosed |
| US-20040176365-A1 | Pde IV inhibitors | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
| EP-1403270-A1 | PDE IV INHIBITORS | Grelan Pharmaceutical Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| EP-1236725-B1 | NOVEL 1,8-NAPHTHYRIDIN-2(1H)-ONE DERIVATIVES | GRELAN PHARMACEUTICAL CO (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6642250-B2 | As phosphodiesterase inhibitor for prophylaxis and therapy of bronchial asthma; pneumonic diseases, pulmonary emphysema, chronic obstructive pulmonary disease acute respiratory distress syndrome (ARDS), and other respiratory diseases | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| CN-1407984-A | Novel 1, 8-naphthyridin-2 (1H) -one derivatives | GRELAN PHARMACEUTICAL CO (JP) | 2003-04-02 | — | — | CN | disclosed |
| US-20030036651-A1 | Novel 1,8-naphthyridin-2(1h)-one derivatives | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-20 | — | — | US | disclosed |
| EP-1236725-A1 | NOVEL 1,8-NAPHTHYRIDIN-2(1H)-ONE DERIVATIVES | Grelan Pharmaceutical Co., Ltd. (JP) | 2002-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176365-A1 | Pde IV inhibitors | PDE3B, PDE3A, PDE2A | CYP4Z1 480/4885CYP4F2 483/4885CYP4A11 34/4885 |
| US-20080085273-A1 | VEHICLE FOR THE TRANSPORT OF A CHOSEN MOLECULE TO A CELL | EPCAM, CD44, SELE | CYP4Z1 3917/4885CYP4F2 2617/4885CYP4A11 3874/4885 |
| US-20030036651-A1 | Novel 1,8-naphthyridin-2(1h)-one derivatives | PDE3B, PDE4A, PDE4B | CYP4Z1 538/4885CYP4F2 705/4885CYP4A11 32/4885 |
| US-20070099969-A1 | Design and synthesis of optimized ligands for ppar | PPARD, PPARA, PPARG | CYP4Z1 700/4885CYP4F2 791/4885CYP4A11 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.