SCHEMBL4958008

SCHEMBL4958008

CCCc1cc(CCC)c(O)c(C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 8/20 0.50
PTPN2 P17706 3/20 0.50
PTPN6 P29350 3/20 0.50
MCL1 Q07820 1/20 0.47
HMGB1 P09429 2/20 0.47
CXCL12 P48061 1/20 0.47
PTPN11 Q06124 2/20 0.45
KAT8 Q9H7Z6 2/20 0.44
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
PPARA Q07869 1/20 0.41
METAP2 P50579 1/20 0.40
LCK P06239 1/20 0.39
KLKB1 P03952 1/20 0.38
CTSB P07858 1/20 0.38
MMP9 P14780 1/20 0.38
DNMT1 P26358 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24114707 0.88 PTPN1 (0.46) PTPN1PTPN2PTPN6MCL1HMGB1
SCHEMBL211842 0.86 KAT8 (0.53) PTPN1PTPN2PTPN6HMGB1CXCL12
SCHEMBL8981485 0.85 KAT8 (0.59) PTPN1PTPN2PTPN6KAT8AKR1C2
SCHEMBL9133047 0.85 KAT8 (0.51) PTPN1PTPN2PTPN6HMGB1CXCL12
SCHEMBL9133045 0.85 KAT8 (0.51) PTPN1PTPN2PTPN6HMGB1CXCL12
SCHEMBL11478526 0.85 KAT8 (0.51) PTPN1PTPN2PTPN6HMGB1CXCL12
SCHEMBL11477238 0.85 KAT8 (0.51) PTPN1PTPN2PTPN6HMGB1CXCL12
SCHEMBL11477241 0.85 KAT8 (0.51) PTPN1PTPN2PTPN6HMGB1CXCL12
SCHEMBL9652558 0.84 PTPN1 (0.75) PTPN1PTPN2PTPN6MCL1HMGB1
SCHEMBL9652220 0.84 PTPN1 (0.75) PTPN1PTPN2PTPN6HMGB1CXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 EP disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 WO disclosed
US-20070010400-A1 Use of color changing indicators in consumer products C2C TECHNOLOGIES, LLC 2007-01-11 US disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 US disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105260-A1 ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105261-A1 CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105191-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
EP-0928994-B1 Toner preparation process XEROX CORP (US) 2004-05-06 EP disclosed
EP-0928994-A2 Toner preparation processes Xerox Corporation (US) 1999-07-14 EP disclosed
US-5902710-A Toner processes XEROX CORPORATION (US) 1999-05-11 US disclosed
US-5869216-A LATEX, AGGREGATION, FUSION/COALESCENCE, SURFACE TREATMENT WITH A SALICYLIC ACID OR A CATECHOL XEROX CORPORATION (US) 1999-02-09 US disclosed
US-5827633-A Toner processes XEROX CORPORATION (US) 1998-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR PTPN1 940/4885PTPN2 974/4885PTPN6 1202/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT PTPN1 663/4885PTPN2 303/4885PTPN6 439/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 PTPN1 4174/4885PTPN2 4419/4885PTPN6 4329/4885
US-20070010400-A1 Use of color changing indicators in consumer products NQO2, CA4, CA7 PTPN1 1330/4885PTPN2 1034/4885PTPN6 1305/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH PTPN1 4466/4885PTPN2 4445/4885PTPN6 4302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.