Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963062 | 0.87 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPTHTTMAPK1 | |
| SCHEMBL4958190 | 0.84 | MGLL (0.42) | KMT2AALDH1A1MEN1MGLLSMN1; SMN2 | |
| SCHEMBL4957412 | 0.83 | FAAH (0.47) | KMT2AALDH1A1L3MBTL1MEN1FAAH | |
| SCHEMBL4958443 | 0.81 | POLB (0.39) | ALDH1A1FAAHSMN1; SMN2TSHRNPC1 | |
| SCHEMBL4959706 | 0.81 | MGLL (0.46) | KMT2AMEN1FAAHMGLL | |
| SCHEMBL4958259 | 0.80 | FAAH (0.41) | KMT2AALDH1A1MEN1FAAHMGLL | |
| SCHEMBL4960982 | 0.79 | HSD11B1 (0.48) | KMT2AALDH1A1HTTMGLLLMNA | |
| SCHEMBL4958536 | 0.79 | FAAH (0.41) | KMT2AL3MBTL1MEN1FAAH | |
| SCHEMBL25345950 | 0.79 | POLB (0.41) | KMT2AALDH1A1MAPTMAPK1MEN1 | |
| SCHEMBL4960190 | 0.79 | POLB (0.41) | KMT2AALDH1A1MAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |