Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.31 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496358 | 0.92 | CHEK1 (0.36) | MEN1ALDH1A1KMT2ASCN9ACHEK1 | |
| SCHEMBL495955 | 0.92 | MEN1 (0.33) | MEN1ALDH1A1KMT2ASCN9ACISD1 | |
| SCHEMBL496465 | 0.84 | MEN1 (0.41) | MEN1ALDH1A1KMT2A | |
| SCHEMBL495888 | 0.84 | MEN1 (0.41) | MEN1ALDH1A1KMT2A | |
| SCHEMBL496442 | 0.79 | FER (0.34) | MEN1KMT2ACISD1CA12CA1 | |
| SCHEMBL17745697 | 0.74 | JAK2 (0.33) | — | |
| SCHEMBL496194 | 0.73 | CHEK1 (0.40) | ALDH1A1CHEK1RPS6KA3SRPK1 | |
| SCHEMBL14976231 | 0.70 | JAK3 (0.42) | CHEK1RPS6KA3SRPK1 | |
| SCHEMBL4368419 | 0.69 | FER (0.36) | MEN1KMT2ACHEK1RPS6KA3SRPK1 | |
| SCHEMBL14638383 | 0.68 | AR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106190-B2 | 2-aminobenzamide derivatives | ASTELLAS PHARMA INC. (JP) | 2012-01-31 | — | — | US | disclosed |