Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959933 | 0.78 | CYP1A2 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2CASP1 | |
| SCHEMBL4958150 | 0.73 | KMT2A (0.40) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL4312797 | 0.69 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL27610366 | 0.67 | MAPT (0.74) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL4960354 | 0.67 | ERCC1 (0.40) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL11947653 | 0.66 | POLB (0.54) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL20883025 | 0.66 | MAPT (0.51) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL4304707 | 0.65 | KMT2A (0.40) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL9727540 | 0.65 | NPSR1 (0.68) | MAPTLMNASMN1; SMN2NPSR1KMT2A | |
| SCHEMBL2296836 | 0.64 | CACNA1G (0.48) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |