Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622279 | 0.84 | NFKB1 (0.37) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| Trifluoroacetic Acid SCHEMBL4622276 | 0.81 | PRKAB2 (0.39) | L3MBTL1TDP1MAPTTHRBNFKB1 | |
| SCHEMBL8255768 | 0.75 | PRKAB2 (0.41) | L3MBTL1TDP1CA2NFKB1NFKB2 | |
| SCHEMBL14112625 | 0.75 | PRKAB2 (0.41) | L3MBTL1TDP1CA2NFKB1NFKB2 | |
| SCHEMBL4621228 | 0.75 | PRKAB2 (0.41) | L3MBTL1TDP1CA2NFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL4621669 | 0.74 | PRKAB2 (0.40) | L3MBTL1TDP1CA2NFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL4619793 | 0.74 | PRKAB2 (0.40) | L3MBTL1TDP1CA2NFKB1NFKB2 | |
| SCHEMBL4621704 | 0.73 | CA2 (0.43) | L3MBTL1TDP1MAPTCA2HTR1A | |
| SCHEMBL4621993 | 0.73 | CA2 (0.43) | L3MBTL1TDP1MAPTCA2HTR1A | |
| SCHEMBL14112641 | 0.72 | AQP1 (0.50) | CA2NFKB1NFKB2RELAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874756-A1 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | Wyeth (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006116165-A1 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |