Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226848 | 0.90 | GPR52 (0.42) | TDP1KDM4EGPR52ALDH1A1ATM | |
| SCHEMBL13992999 | 0.83 | AQP1 (0.45) | MTNR1ACYP3A4TSHRALDH1A1MTNR1B | |
| SCHEMBL4596110 | 0.79 | GPR52 (0.39) | TDP1KDM4EGPR52ALDH1A1ATM | |
| SCHEMBL4225706 | 0.78 | PRKAB2 (0.54) | TDP1GPR52ATMPRKAB2PRKAG1 | |
| SCHEMBL5791592 | 0.78 | PRKAB2 (0.54) | TDP1GPR52ATMPRKAB2PRKAG1 | |
| SCHEMBL13992998 | 0.78 | AQP1 (0.53) | MTNR1ACYP3A4GPR52MTNR1BCYP2C19 | |
| SCHEMBL4231359 | 0.78 | AQP1 (0.45) | TDP1KDM4EGPR52ALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL6000525 | 0.78 | PRKAB2 (0.44) | MTNR1ACYP3A4TSHRALDH1A1MTNR1B | |
| SCHEMBL4959672 | 0.77 | AQP1 (0.53) | MTNR1AKDM4ECYP1A2ALDH1A1MTNR1B | |
| SCHEMBL4964699 | 0.77 | AQP1 (0.43) | MTNR1AMTNR1BPRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470799-B2 | Dihydrobenzofuran derivatives and uses thereof | WYETH (US) | 2008-12-30 | — | — | US | disclosed |
| US-7470799-B2 | Dihydrobenzofuran derivatives and uses thereof | WYETH (US) | 2008-12-30 | — | — | US | disclosed |
| US-7470799-B2 | Dihydrobenzofuran derivatives and uses thereof | WYETH (US) | 2008-12-30 | — | — | US | disclosed |
| EP-1871754-A1 | DIHYDROBENZOFURAN DERIVATIVES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006116136-A1 | DIHYDROBENZOFURAN DERIVATIVES AND USES THEREOF | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |
| US-20060246551-A1 | Dihydrobenzofuran derivatives and uses thereof | WYETH (US) | 2006-11-02 | — | — | US | disclosed |