SCHEMBL4960164

SCHEMBL4960164

O=C(O)c1cccc(C(F)(F)C(F)(F)C(F)F)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
ALOX15 P16050 2/20 0.41
LMNA P02545 1/20 0.39
TAS2R14 Q9NYV8 2/20 0.38
AKR1C3 P42330 1/20 0.38
FABP4 P15090 1/20 0.38
CDC25B P30305 3/20 0.37
ALB P02768 1/20 0.36
MAPT P10636 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
KMT2A Q03164 3/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
MEN1 O00255 1/20 0.35
CDC25A P30304 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ATM Q13315 1/20 0.34
PRNP P04156 1/20 0.34
POLB P06746 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20483740 0.86 ALDH1A1 (0.52) ALDH1A1ALOX15LMNATAS2R14AKR1C3
SCHEMBL7095723 0.84 ALOX15 (0.43) ALDH1A1ALOX15LMNATAS2R14AKR1C3
SCHEMBL3822237 0.81 ALOX15 (0.42) ALDH1A1ALOX15LMNATAS2R14AKR1C3
SCHEMBL9013418 0.79 ALDH1A1 (0.44) ALDH1A1ALOX15LMNATAS2R14AKR1C3
SCHEMBL2964734 0.79 TAS2R14 (0.51) ALDH1A1ALOX15LMNATAS2R14AKR1C3
SCHEMBL8977522 0.79 TAS2R14 (0.39) ALDH1A1ALOX15LMNATAS2R14AKR1C3
SCHEMBL7096331 0.79 TAS2R14 (0.39) ALDH1A1ALOX15LMNATAS2R14AKR1C3
SCHEMBL27075282 0.78 TAS2R14 (0.50) ALDH1A1ALOX15LMNATAS2R14FABP4
SCHEMBL7091349 0.77 TAS2R14 (0.38) ALDH1A1ALOX15LMNATAS2R14AKR1C3
SCHEMBL7092199 0.77 TAS2R14 (0.38) ALDH1A1ALOX15LMNATAS2R14AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651332-B1 SOLVENT RESISTANT ASYMMETRIC INTEGRALLY SKINNED MEMBRANES VAPERMA INC (CA) 2008-06-25 EP claimed
EP-0668886-A1 AQUEOUS SIZE FOR FIBER REINFORCED HIGH TEMPERATURE COMPOSITES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-08-30 EP claimed
WO-1994011419-A1 AQUEOUS SIZE FOR FIBER REINFORCED HIGH TEMPERATURE COMPOSITES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-05-26 WO claimed
US-6891067-B2 Optical polyimide precursor, optical polyimide compound and fabricating method thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-05-10 US disclosed
US-20030065128-A1 Optical polyimide precursor, optical polyimide compound and fabricating method thereof YOU KYUNG-HEE (KR) 2003-04-03 US disclosed
US-6486292-B2 CORE, CLADDING STRUCTURE SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-11-26 US disclosed
US-20010023286-A1 Optical polyimide precursor, optical polyimide compound and fabricating method thefeof SAMSUNG ELECTRONICS CO., LTD. (KR) 2001-09-20 US disclosed
EP-0668886-A1 AQUEOUS SIZE FOR FIBER REINFORCED HIGH TEMPERATURE COMPOSITES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-08-30 EP disclosed
WO-1994011419-A1 AQUEOUS SIZE FOR FIBER REINFORCED HIGH TEMPERATURE COMPOSITES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-05-26 WO disclosed
EP-0595959-A1 A METHOD FOR FORMING AND CONSOLIDATING A FIBER REINFORCED RESIN STRUCTURE. DU PONT (US) 1994-05-11 EP disclosed
WO-1993001925-A1 A METHOD FOR FORMING AND CONSOLIDATING A FIBER REINFORCED RESIN STRUCTURE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010023286-A1 Optical polyimide precursor, optical polyimide compound and fabricating method thefeof POF1B, GTF2F1, MACF1 ALDH1A1 4796/4885ALOX15 2490/4885LMNA 3020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.