Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.44 |
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP3 | P08254 | 6/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27182937 | 1.00 | MMP1 (0.44) | MMP1MMP2MMP3CTSSCTSK | |
| SCHEMBL9146946 | 0.86 | LTA4H (0.50) | MMP1MMP2MMP3CPB2LTA4H | |
| SCHEMBL9146938 | 0.86 | LTA4H (0.50) | MMP1MMP2MMP3CPB2LTA4H | |
| SCHEMBL7205806 | 0.85 | MMP1 (0.58) | MMP1MMP2MMP3CTSSCTSK | |
| Hydrochloric Acid SCHEMBL7205132 | 0.83 | MMP1 (0.57) | MMP1MMP2MMP3CTSSCTSK | |
| SCHEMBL7204995 | 0.83 | MMP2 (0.50) | MMP1MMP2MMP3CTSSCTSK | |
| Hydrochloric Acid SCHEMBL7205141 | 0.82 | MMP2 (0.49) | MMP1MMP2MMP3CTSSCTSK | |
| SCHEMBL10793999 | 0.82 | CASP3 (0.34) | MMP1MMP2MMP3ITGB3ITGA2B | |
| SCHEMBL10787451 | 0.82 | CASP3 (0.34) | MMP1MMP2MMP3ITGB3ITGA2B | |
| SCHEMBL25523633 | 0.81 | CTSK (0.45) | CTSSCTSKCPB2LTA4HCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114828-B1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | AJINOMOTO KK (JP) | 2008-03-12 | — | — | EP | disclosed |
| EP-1114828-A1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-07-11 | — | — | EP | disclosed |
| EP-0759030-B1 | N- N-(3,3-DIMETHYLBUTYL)-L-$g(a)-ASPARTYL]-L-HEXAHYDROPHENYLALANINE 1-METHYL ESTER USEFUL AS A SWEETENING AGENT AND METHOD OF PREPARATION | NOFRE CLAUDE (FR) | 1998-09-09 | — | — | EP | disclosed |
| US-5773640-A | N- N-(3,3-dimethylbutyl)-L-A-aspartyl!-L-hexahydrophenylalanine 1-methyl ester useful as a sweetening agent, its method of preparation | NOFRE CLAUDE (FR) | 1998-06-30 | — | — | US | disclosed |
| US-4371464-A | Dipeptide sweetener | STAMICARBON, B.V. (NL) | 1983-02-01 | — | — | US | disclosed |
| EP-0048051-A1 | Dipeptide sweetener | STAMICARBON B.V. (NL) | 1982-03-24 | — | — | EP | disclosed |
| US-4170635-A | DIPEPTIDE SWEETENER, ANHYDRIDE | COLGATE PALMOLIVE COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4071615-A | DIPEPTIDE SWEETENER | COLGATE PALMOLIVE COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-3939261-A | DIPEPTIDE SWEETENER, ACID ANHYDRIDE | COLGATE-PALMOLIVE COMPANY (US) | 1976-02-17 | — | — | US | disclosed |