Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418885 | 0.88 | LTB4R (0.65) | LTB4RLTB4R2APPALDH1A1PKM | |
| SCHEMBL8565773 | 0.86 | LTB4R (0.53) | LTB4RLTB4R2APPALDH1A1PKM | |
| SCHEMBL8422218 | 0.84 | LTB4R (0.50) | LTB4RLTB4R2APPALDH1A1PKM | |
| SCHEMBL8418898 | 0.84 | LTB4R (0.65) | LTB4RLTB4R2APPALDH1A1PTGER1 | |
| SCHEMBL8418922 | 0.82 | LTB4R (0.57) | LTB4RLTB4R2ALDH1A1PTGER1MAPT | |
| SCHEMBL8418430 | 0.78 | LTB4R (0.52) | LTB4RLTB4R2APPALDH1A1PKM | |
| SCHEMBL8422344 | 0.77 | LTB4R (0.53) | LTB4RLTB4R2PKMPTGER1MAPT | |
| SCHEMBL8564500 | 0.76 | LTB4R (0.65) | LTB4RLTB4R2APPALDH1A1MAPT | |
| SCHEMBL8420359 | 0.76 | LTB4R (0.52) | LTB4RLTB4R2LMNA | |
| SCHEMBL8420802 | 0.73 | LTB4R (0.46) | LTB4RLTB4R2APPALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888033-A2 | METHOD AND COMPOSITION FOR TREATING INFLAMMATORY DISORDERS | Biolipox AB (SE) | 2008-02-20 | — | — | EP | disclosed |
| EP-1742622-A1 | USE OF LTB4 INHIBITORS FOR THE TREATMENT OF B-CELL LEUKEMIAS AND LYMPHOMAS | Biolipox AB (SE) | 2007-01-17 | — | — | EP | disclosed |
| WO-2006131737-A2 | METHOD AND COMPOSITION FOR TREATING INFLAMMATORY DISORDERS | BIOLIPOX AB (SE) | 2006-12-14 | — | — | WO | disclosed |
| WO-2005107725-A1 | USE OF LTB4 INHIBITORS FOR THE TREATMENT OF B-CELL LEUKEMIAS AND LYMPHOMAS | BIOLIPOX AB (SE) | 2005-11-17 | — | — | WO | disclosed |