SCHEMBL4962265

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4962833	0.81	SMN1; SMN2 (0.54)	KMT2AALDH1A1SMN1; SMN2KDM4EGAA
	SCHEMBL4963409	0.79	TRPA1 (0.52)	ALDH1A1SMN1; SMN2TRPA1CYP3A4CYP2C9
	SCHEMBL4963420	0.79	TRPA1 (0.52)	ALDH1A1SMN1; SMN2TRPA1CYP3A4CYP2C9
	SCHEMBL8149545	0.76	MEN1 (0.67)	MEN1KMT2AALDH1A1SMN1; SMN2NPY1R
	SCHEMBL14491540	0.75	SMN1; SMN2 (0.55)	MEN1KMT2AALDH1A1SMN1; SMN2HTT
	SCHEMBL6553912	0.74	CYP2D6 (0.61)	MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9
	SCHEMBL6938286	0.72	CYP1A2 (0.63)	MEN1KMT2ASMN1; SMN2NPY1RCYP1A2
	SCHEMBL11099777	0.72	MEN1 (0.55)	MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9
	SCHEMBL433860	0.71	P2RX7 (0.55)	TRPA1CYP3A4CYP2C9CYP2C19CYP2D6
	SCHEMBL6630527	0.71	CYP2D6 (0.58)	MEN1KMT2AALDH1A1SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.