Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963944 | 0.94 | P2RX7 (0.47) | FAAHEPHX1RAB9AALDH1A1NPC1 | |
| SCHEMBL4962238 | 0.91 | FAAH (0.70) | FAAHEPHX1RAB9AALDH1A1 | |
| SCHEMBL5517974 | 0.91 | FAAH (0.70) | FAAHEPHX1RAB9AALDH1A1 | |
| SCHEMBL4964213 | 0.85 | ALDH1A1 (0.59) | FAAHEPHX1RAB9AALDH1A1NPC1 | |
| SCHEMBL4962789 | 0.82 | FAAH (0.70) | FAAHEPHX1RAB9AALDH1A1NPC1 | |
| SCHEMBL14470481 | 0.79 | EPHX1 (0.65) | FAAHEPHX1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL1690685 | 0.75 | FAAH (1.00) | FAAHEPHX1RAB9AALDH1A1 | |
| SCHEMBL4963922 | 0.73 | PRMT3 (0.50) | FAAHEPHX1NPC1 | |
| SCHEMBL4965304 | 0.73 | EPHX1 (0.70) | EPHX1NPC1MAPT | |
| SCHEMBL5520154 | 0.72 | RAB9A (0.45) | FAAHRAB9AALDH1A1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1969051-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. Organon (NL) | 2008-09-17 | — | — | EP | disclosed |
| WO-2008024139-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. ORGANON (NL) | 2008-02-28 | — | — | WO | disclosed |
| WO-2007079180-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. ORGANON (NL) | 2007-07-12 | — | — | WO | disclosed |