SCHEMBL4963704

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4963846	0.84	OPRM1 (0.43)	OPRM1OPRD1OPRK1PARP10PARP15
	SCHEMBL4964185	0.83	MAPK1 (0.44)	OPRM1OPRD1OPRK1ALDH1A1KMT2A
	Hydrochloric Acid SCHEMBL4964496	0.82	MAPK1 (0.43)	OPRM1OPRD1OPRK1ALDH1A1KMT2A
	SCHEMBL4964019	0.81	SLC8A1 (0.50)	OPRM1OPRD1OPRK1PARP10PARP15
	SCHEMBL4964763	0.81	OPRM1 (0.69)	OPRM1OPRD1OPRK1PARP10KMT2A
	SCHEMBL12607762	0.80	RORC (0.50)	OPRM1OPRD1OPRK1PARP10CA2
	SCHEMBL4965706	0.79	OPRM1 (0.43)	OPRM1OPRD1OPRK1KMT2ACA2
	SCHEMBL4963842	0.79	OPRM1 (0.48)	OPRM1OPRD1OPRK1PARP10PARP15
	SCHEMBL4965157	0.79	PARP10 (0.46)	OPRM1OPRD1OPRK1PARP10PARP15
	SCHEMBL4963401	0.77	OPRM1 (0.43)	OPRM1OPRD1OPRK1PARP10PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.