SCHEMBL4963752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4964061	0.89	OPRM1 (0.41)	HDAC6F2OPRM1OPRD1OPRK1
	SCHEMBL4965288	0.80	OPRM1 (0.46)	OPRM1OPRD1OPRK1ALDH1A1
	SCHEMBL4963746	0.76	HRH3 (0.48)	OPRM1KMT2AMEN1
	SCHEMBL4965706	0.76	OPRM1 (0.43)	HDAC1OPRM1OPRD1OPRK1KMT2A
	SCHEMBL14132128	0.76	OPRM1 (0.67)	OPRM1OPRD1OPRK1KMT2AALDH1A1
	SCHEMBL4964102	0.76	OPRM1 (0.43)	HDAC6HDAC3HDAC4HDAC1HDAC8
	SCHEMBL4963716	0.75	LTA4H (0.55)	HDAC1OPRM1OPRD1OPRK1KMT2A
	SCHEMBL3090215	0.75	HDAC6 (0.71)	HDAC6HDAC3HDAC4HDAC1HDAC8
	SCHEMBL4964806	0.74	OPRM1 (0.41)	HDAC6HDAC3HDAC4HDAC1HDAC8
	SCHEMBL8826390	0.73	HTT (0.58)	HDAC6HDAC3HDAC4HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.