SCHEMBL4964575

SCHEMBL4964575

O=C(CS(=O)(=O)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 7/20 0.59
RECQL P46063 2/20 0.59
LMNA P02545 1/20 0.57
ALDH1A1 P00352 3/20 0.55
PKM P14618 2/20 0.55
KMT2A Q03164 3/20 0.54
MAPT P10636 1/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
PTPN1 P18031 1/20 0.50
CA2 P00918 1/20 0.50
MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4966036 0.91 RECQL (0.73) HSD11B1RECQLLMNAALDH1A1KMT2A
SCHEMBL4964735 0.86 HSD11B1 (0.50) HSD11B1RECQLLMNAALDH1A1PKM
SCHEMBL4965634 0.83 RECQL (0.54) HSD11B1RECQLALDH1A1KMT2AMAPT
SCHEMBL29012562 0.82 HSD11B1 (0.83) HSD11B1RECQLLMNAALDH1A1PKM
SCHEMBL6203276 0.82 HSD11B1 (0.83) HSD11B1RECQLLMNAALDH1A1PKM
SCHEMBL28701120 0.79 NPC1 (0.54) RECQLLMNAALDH1A1PKMMAPT
SCHEMBL1981537 0.79 MMP2 (0.66) HSD11B1LMNAKMT2ACA2
SCHEMBL10932088 0.78 HSD11B1 (0.61) HSD11B1RECQLLMNAALDH1A1PKM
SCHEMBL452973 0.78 HSD11B1 (0.77) HSD11B1RECQLALDH1A1KMT2AMAPT
SCHEMBL7385583 0.78 ALDH1A1 (0.67) HSD11B1RECQLLMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7012159-B1 Phenolic compounds and recording materials containing the same NIPPON SODA CO., LTD. (JP) 2006-03-14 US claimed
EP-1967514-B1 Phenolic compounds and recording materials containing the same NIPPON SODA CO (JP) 2013-01-02 EP disclosed
EP-1967514-A1 Phenolic compounds and recording materials containing the same Nippon Soda Co., Ltd. (JP) 2008-09-10 EP disclosed
US-7012159-B1 Phenolic compounds and recording materials containing the same NIPPON SODA CO., LTD. (JP) 2006-03-14 US disclosed
EP-1219598-A1 PHENOLIC COMPOUNDS AND RECORDING MATERIALS CONTAINING THE SAME NIPPON SODA CO., LTD. (JP) 2002-07-03 EP disclosed