SCHEMBL4964735

SCHEMBL4964735

O=C(CS(=O)(=O)c1ccc(O)cc1)c1ccc(O)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 5/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 4/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 2/20 0.47
PLAA Q9Y263 1/20 0.46
RECQL P46063 1/20 0.46
CA2 P00918 1/20 0.46
KDM4E B2RXH2 1/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.46
ALPG P10696 1/20 0.45
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6200420 0.87 HSD11B1 (0.66) HSD11B1ALDH1A1MAPTKMT2ANPC1
SCHEMBL4964575 0.86 HSD11B1 (0.59) HSD11B1ALDH1A1MAPTKMT2ANPC1
SCHEMBL4965634 0.81 RECQL (0.54) HSD11B1ALDH1A1MAPTKMT2ANPC1
SCHEMBL4966036 0.78 RECQL (0.73) HSD11B1ALDH1A1MAPTKMT2ANPC1
SCHEMBL4964662 0.72 CYP19A1 (0.53) HSD11B1ALDH1A1KMT2AMEN1RECQL
SCHEMBL1981537 0.71 MMP2 (0.66) HSD11B1KMT2ACA2LMNA
SCHEMBL6203276 0.70 HSD11B1 (0.83) HSD11B1ALDH1A1KMT2ANPC1RAB9A
SCHEMBL29012562 0.70 HSD11B1 (0.83) HSD11B1ALDH1A1MAPTKMT2ANPC1
SCHEMBL7385583 0.70 ALDH1A1 (0.67) HSD11B1ALDH1A1MAPTKMT2ANPC1
SCHEMBL31509307 0.69 CA12 (0.58) MAPTKMT2AMEN1PLAARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1967514-B1 Phenolic compounds and recording materials containing the same NIPPON SODA CO (JP) 2013-01-02 EP disclosed
EP-1967514-A1 Phenolic compounds and recording materials containing the same Nippon Soda Co., Ltd. (JP) 2008-09-10 EP disclosed
US-7012159-B1 Phenolic compounds and recording materials containing the same NIPPON SODA CO., LTD. (JP) 2006-03-14 US disclosed
EP-1219598-A1 PHENOLIC COMPOUNDS AND RECORDING MATERIALS CONTAINING THE SAME NIPPON SODA CO., LTD. (JP) 2002-07-03 EP disclosed