Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964869 | 0.89 | SLC6A4 (0.41) | HRH1 | |
| SCHEMBL4964731 | 0.81 | KIT (0.42) | HRH1 | |
| SCHEMBL4964913 | 0.80 | SCN9A (0.37) | HRH1 | |
| SCHEMBL4966050 | 0.79 | GABRA1 (0.38) | HRH1 | |
| Hydrochloric Acid SCHEMBL4966442 | 0.78 | GABRA1 (0.38) | HRH1 | |
| Hydrochloric Acid SCHEMBL4964910 | 0.77 | KIT (0.39) | — | |
| SCHEMBL4966480 | 0.74 | TAAR1 (0.46) | — | |
| SCHEMBL4964287 | 0.73 | HRH1 (0.43) | HRH1 | |
| SCHEMBL4965972 | 0.72 | HTR6 (0.44) | — | |
| SCHEMBL4963979 | 0.72 | IDH1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904483-A1 | BENZIMIDAZOLE DERIVATIVES AS 5-HT6,5-HT24 | F. Hoffmann-Roche AG (CH) | 2008-04-02 | — | — | EP | claimed |
| WO-2007006677-A1 | BENZIMIDAZOLE DERIVATIVES AS 5-HT6,5-HT24 | F. HOFFMANN-LA ROCHE AG (CH) | 2007-01-18 | — | — | WO | claimed |
| EP-1904483-A1 | BENZIMIDAZOLE DERIVATIVES AS 5-HT6,5-HT24 | F. Hoffmann-Roche AG (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006677-A1 | BENZIMIDAZOLE DERIVATIVES AS 5-HT6,5-HT24 | F. HOFFMANN-LA ROCHE AG (CH) | 2007-01-18 | — | — | WO | disclosed |