Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM1A | O60341 | 3/20 | 0.59 |
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | DDX3X | O00571 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966898 | 0.89 | MEN1 (0.60) | MEN1KMT2AKDM1ALMNAMAOA | |
| SCHEMBL4965534 | 0.85 | SMN1; SMN2 (0.53) | MEN1KMT2AKDM1AKMOMAOA | |
| SCHEMBL4963059 | 0.84 | ALDH1A1 (0.54) | MEN1KMT2AKDM1ALMNAALDH1A1 | |
| SCHEMBL4966172 | 0.83 | VCAM1 (0.52) | MEN1KMT2AKDM1ALMNAMAOA | |
| SCHEMBL4966790 | 0.83 | KDM1A (0.45) | MEN1KMT2AKDM1AMAOAALDH1A1 | |
| SCHEMBL4962685 | 0.82 | MEN1 (0.60) | MEN1KMT2AKDM1ALMNAMAOA | |
| SCHEMBL4964673 | 0.82 | KDM1A (0.53) | MEN1KMT2AKDM1AMAOAALDH1A1 | |
| SCHEMBL4965545 | 0.81 | KMT2A (0.46) | MEN1KMT2AKDM1ALMNAMAOA | |
| SCHEMBL4966051 | 0.81 | KDM1A (0.60) | MEN1KMT2AKDM1ALMNAMAOA | |
| SCHEMBL4965945 | 0.80 | GLO1 (0.48) | MEN1KMT2AKDM1AMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888544-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Takeda San Diego, Inc. (US) | 2008-02-20 | — | — | EP | claimed |
| WO-2006066109-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-06-22 | — | — | WO | claimed |
| EP-1888544-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Takeda San Diego, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006066109-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-06-22 | — | — | WO | disclosed |