Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | IKBKB | O14920 | 6/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16750169 | 0.74 | GAA (0.54) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5491089 | 0.70 | ALDH1A1 (0.58) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL27859886 | 0.70 | GAA (0.50) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL28359880 | 0.70 | GAA (0.70) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11644064 | 0.69 | JAK2 (0.69) | IKBKB | |
| Formamide SCHEMBL28359882 | 0.69 | GAA (0.87) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15681582 | 0.68 | MAPT (0.52) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL20862830 | 0.67 | IKBKB (0.56) | MEN1KMT2AMAPTIKBKBCYP1A2 | |
| SCHEMBL28229746 | 0.67 | GAA (0.55) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2652713 | 0.67 | GAA (0.50) | GAAALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436279-B8 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1436279-B1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7179836-B2 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1436279-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2005-10-26 | — | — | EP | disclosed |
| US-20040192941-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION | 2004-09-30 | — | — | US | disclosed |
| EP-1436279-A1 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003027093-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192941-A1 | Chemical compounds | TPMT, TST, CYP11B2 | GAA 254/4885ALDH1A1 165/4885MEN1 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.