SCHEMBL4965564

SCHEMBL4965564

C=C(C(=O)Oc1ccc(C=C(C=Cc2ccccc2)C=Cc2ccc(OC(C)OCC)cc2)cc1)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.39
KMT2A Q03164 6/20 0.38
MEN1 O00255 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 2/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
PPARA Q07869 2/20 0.35
EGFR P00533 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HPGD P15428 1/20 0.35
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4964733 0.93 LTB4R (0.38) LTB4RLTB4R2KMT2AMEN1NPC1
SCHEMBL4967554 0.85 BCHE (0.34) LTB4RLTB4R2KMT2AMEN1NPC1
SCHEMBL5702566 0.82 LTB4R (0.37) LTB4RLTB4R2KMT2AMEN1NPC1
SCHEMBL7199294 0.81 LTB4R (0.41) LTB4RLTB4R2KMT2ANPC1RAB9A
SCHEMBL3842067 0.81 LTB4R (0.41) LTB4RLTB4R2KMT2ANPC1RAB9A
SCHEMBL5702546 0.79 CA12 (0.38) LTB4RLTB4R2KMT2AMEN1NPC1
SCHEMBL7103538 0.79 CA12 (0.38) LTB4RLTB4R2KMT2AMEN1NPC1
SCHEMBL4964310 0.79 KMT2A (0.47) LTB4RLTB4R2KMT2AMEN1NPC1
SCHEMBL7106818 0.78 CA12 (0.36) LTB4RLTB4R2KMT2AMEN1NPC1
SCHEMBL6842075 0.77 ABCG2 (0.39) LTB4RLTB4R2KMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1314725-B1 SULFONIUM SALT COMPOUND WAKO PURE CHEM IND LTD (JP) 2008-03-19 EP disclosed
US-6924323-B2 Sulfonium salt compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 US disclosed
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
US-20040033434-A1 Sulfonium salt compound FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2004-02-19 US disclosed
EP-1314725-A1 SULFONIUM SALT COMPOUND Wako Pure Chemical Industries, Ltd. (JP) 2003-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040033434-A1 Sulfonium salt compound SPIN1, RER1, SPIN2B LTB4R 4328/4885LTB4R2 4242/4885KMT2A 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.