SCHEMBL4964310

SCHEMBL4964310

CCOC(C)Oc1ccc(C=C(C=Cc2ccc(O)cc2)C=Cc2ccc(OC(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.47
MAPT P10636 4/20 0.47
KDM4E B2RXH2 2/20 0.47
HSP90AA1 P07900 2/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 3/20 0.42
NPC1 O15118 1/20 0.42
ABCG2 Q9UNQ0 3/20 0.42
MAOB P27338 1/20 0.42
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
LMNA P02545 1/20 0.40
CYP3A4 P08684 1/20 0.40
HSPD1 P10809 1/20 0.40
PKM P14618 1/20 0.40
NFKB1 P19838 1/20 0.40
HSPE1 P61604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7199294 0.89 LTB4R (0.41) KMT2AMAPTRAB9ANPC1ABCG2
SCHEMBL3842067 0.89 LTB4R (0.41) KMT2AMAPTRAB9ANPC1ABCG2
SCHEMBL6842075 0.82 ABCG2 (0.39) KMT2AMAPTMEN1ALDH1A1RAB9A
SCHEMBL3838358 0.82 CA12 (0.43) KMT2AMAPTMEN1ALDH1A1RAB9A
SCHEMBL7270962 0.81 PTGS2 (0.40) KMT2AMAPTKDM4EMEN1ALDH1A1
SCHEMBL7138148 0.81 MAOB (0.42) ABCG2MAOBCA12CA1CA2
SCHEMBL5702546 0.81 CA12 (0.38) KMT2AMAPTMEN1ALDH1A1RAB9A
SCHEMBL7103538 0.81 CA12 (0.38) KMT2AMAPTMEN1ALDH1A1RAB9A
SCHEMBL5702566 0.80 LTB4R (0.37) KMT2AMAPTMEN1ALDH1A1RAB9A
SCHEMBL6553372 0.79 ABCG2 (0.39) KMT2AMAPTMEN1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1314725-B1 SULFONIUM SALT COMPOUND WAKO PURE CHEM IND LTD (JP) 2008-03-19 EP disclosed
US-6924323-B2 Sulfonium salt compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 US disclosed
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
US-20040033434-A1 Sulfonium salt compound FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2004-02-19 US disclosed
US-6656660-B1 Resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-02 US disclosed
US-6586152-B1 Useful as an ingredient of a resist composition used for preparation of semiconductor devices and the like, which comprises a compound shown by the following general formula useful as an ingredient of a resist composition used for WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2003-07-01 US disclosed
EP-1314725-A1 SULFONIUM SALT COMPOUND Wako Pure Chemical Industries, Ltd. (JP) 2003-05-28 EP disclosed
EP-1024406-A1 Resist composition WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 2000-08-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040033434-A1 Sulfonium salt compound SPIN1, RER1, SPIN2B KMT2A 1142/4885MAPT 2666/4885KDM4E 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.