SCHEMBL4965699

SCHEMBL4965699

Cc1ccc(Cc2ccc(Nc3ccc(Cc4ccc(C)cc4C)cc3)cc2)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.46
MEN1 O00255 2/20 0.43
GAA P10253 2/20 0.43
KMT2A Q03164 2/20 0.43
G6PD P11413 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
USP2 O75604 1/20 0.42
MAPT P10636 1/20 0.42
CASP1 P29466 1/20 0.42
HBB P68871 1/20 0.42
HPGD P15428 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SAE1 Q9UBE0 1/20 0.38
UBA2 Q9UBT2 1/20 0.38
PSMB5 P28074 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4624112 0.86 PYCR1 (0.42) KDM4EALDH1A1NPC1RAB9A
SCHEMBL24941721 0.83 HPGD (0.53) RAPGEF4MEN1GAAKMT2AG6PD
SCHEMBL7566966 0.79 ESR1 (0.48) MEN1GAAKMT2AL3MBTL1KDM4E
SCHEMBL10950441 0.79 MAP2K4 (0.41) KMT2AKDM4EALDH1A1NPC1RAB9A
SCHEMBL14407100 0.79 PYCR1 (0.38) KMT2AKDM4EALDH1A1PSMB5
SCHEMBL3301748 0.79 CYP3A4 (0.53) NPC1RAB9APSMB5
SCHEMBL11740944 0.78 HTR2A (0.40) L3MBTL1KDM4EALDH1A1MAPT
SCHEMBL3299248 0.77 PYCR1 (0.47) MEN1GAAKMT2AKDM4EALDH1A1
SCHEMBL28302613 0.76 L3MBTL1 (0.50) L3MBTL1ALDH1A1NPC1RAB9A
SCHEMBL20204976 0.76 TEAD4 (0.42) MEN1KMT2AL3MBTL1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220403150-A1 METHOD FOR PRODUCING VINYL CHLORIDE TYPE POLYMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-12-22 US disclosed
EP-3988584-A1 METHOD FOR PRODUCING VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 2022-04-27 EP disclosed
EP-3988585-A1 METHOD FOR PRODUCING VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 2022-04-27 EP disclosed
EP-1502925-B1 Production process for vinyl chloride polymer SHINETSU CHEMICAL CO (JP) 2008-01-09 EP disclosed
EP-1445265-B1 Process for producing vinyl chloride-based polymer SHINETSU CHEMICAL CO (JP) 2006-04-05 EP disclosed
US-6977288-B2 Production process for vinyl chloride polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-12-20 US disclosed
US-6965002-B2 Process for producing vinyl chloride-based polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-11-15 US disclosed
US-20050027088-A1 Production process for vinyl chloride polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-02-03 US disclosed
EP-1502925-A1 Production process for vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 2005-02-02 EP disclosed
US-20040186257-A1 Heat generated during polymerization is removed using a reflux condenser; ethylene oxide/propylene oxide copolymeric polyether with a weight average molecular weight of 1,500,000 to 2,000,000 is added as an antifoam agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-09-23 US disclosed
EP-1445265-A1 Process for producing vinyl chloride-based polymer Shin-Etsu Chemical Co., Ltd. (JP) 2004-08-11 EP disclosed