Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971087 | 0.87 | MMP13 (0.43) | ALDH1A1LMNAOPRM1 | |
| SCHEMBL3831699 | 0.85 | KMT2A (0.49) | ALDH1A1LMNARAB9A | |
| SCHEMBL12799323 | 0.81 | CTSL (0.60) | CTSL | |
| SCHEMBL2857336 | 0.81 | CA12 (0.56) | EPHX2MASP2APEX1OPRM1OPRL1 | |
| SCHEMBL2857323 | 0.79 | CA12 (0.45) | MASP2APEX1RXFP1CTSL | |
| SCHEMBL12898777 | 0.77 | MASP2 (0.53) | EPHX2MASP2ALDH1A1LMNAAPEX1 | |
| SCHEMBL4966953 | 0.77 | EPHX2 (0.44) | EPHX2APEX1POLBOPRM1OPRL1 | |
| SCHEMBL12884455 | 0.76 | MASP2 (0.52) | EPHX2MASP2ALDH1A1LMNAAPEX1 | |
| SCHEMBL4969822 | 0.76 | CTSS (0.39) | ALDH1A1LMNAOPRM1 | |
| SCHEMBL13575664 | 0.75 | CTSL (0.47) | CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963277-A1 | FLUORINATED COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007076306-A1 | FLUORINATED COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | WO | claimed |