Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484876 | 0.78 | L3MBTL1 (0.53) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL15404712 | 0.74 | ENPP1 (0.43) | L3MBTL1TLR8EGFR | |
| SCHEMBL9476831 | 0.71 | KDM1A (0.44) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL16574198 | 0.70 | KDM1A (0.46) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL10976808 | 0.69 | CYP17A1 (0.48) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL5865754 | 0.69 | L3MBTL1 (0.53) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL8993383 | 0.69 | MGLL (0.49) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL8993210 | 0.69 | ERN1 (0.56) | KDM4EMEN1MAPTMAPK1KMT2A | |
| SCHEMBL13756275 | 0.67 | RXRA (0.47) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL11063154 | 0.67 | CYP17A1 (0.46) | KDM4EMEN1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981876-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | Arrow Therapeutics Limited (GB) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007080401-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2007-07-19 | — | — | WO | disclosed |