Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716749 | 0.83 | AGTR1 (0.41) | NR4A3ALKBH1L3MBTL1 | |
| SCHEMBL23319033 | 0.80 | LMNA (0.53) | RAB9ASMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL3580133 | 0.79 | LMNA (0.54) | POLBRAB9ASMN1; SMN2NR4A3HTT | |
| SCHEMBL15565711 | 0.79 | NPC1 (0.46) | POLBRAB9ASMN1; SMN2NR4A3HTT | |
| SCHEMBL1406641 | 0.78 | HCAR3 (0.41) | SMN1; SMN2NR4A3ALKBH1ALDH1A1MAPK1 | |
| SCHEMBL2806923 | 0.78 | ALDH1A1 (0.45) | RAB9ASMN1; SMN2NR4A3HTTLMNA | |
| SCHEMBL26135833 | 0.77 | ALKBH1 (0.37) | POLBSMN1; SMN2NR4A3ALKBH1ALDH1A1 | |
| SCHEMBL26133999 | 0.77 | SMN1; SMN2 (0.39) | POLBRAB9ASMN1; SMN2NR4A3HTT | |
| SCHEMBL966692 | 0.76 | KDM4E (0.41) | POLBRAB9ASMN1; SMN2NR4A3HTT | |
| SCHEMBL1407149 | 0.76 | ALKBH1 (0.37) | SMN1; SMN2NR4A3HTTALKBH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737449-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002177-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2025-01-02 | — | — | WO | disclosed |
| EP-1320527-B1 | METHOD FOR PRODUCING 1 SUBSTITUTED 5-CHLORO-4 METHYL PYRAZOLES | BASF SE (DE) | 2008-08-13 | — | — | EP | disclosed |
| US-7002023-B2 | Method for producing 1 substituted 5-chloro-4 methly pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2006-02-21 | — | — | US | disclosed |
| US-20040102505-A1 | Method for producing 1 substituted 5-chloro-4 methly pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-27 | — | — | US | disclosed |
| US-6515139-B1 | A process for preparing N-substituted 2-pyrazolin-5-ones of the formula I h R is C1-C8-alkyl, C5-C8-cycloalkyl, phenyl, naphthyl or phenyl- C1-C4-alkyl which may be unsubstituted or may carry one or more substituents which are inert towards | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102505-A1 | Method for producing 1 substituted 5-chloro-4 methly pyrazoles | CYP4F2, CYP2F1, CYP4F3 | POLB 2749/4885RAB9A 2335/4885SMN1; SMN2 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.