Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25496806 | 1.00 | DGAT1 (0.37) | DGAT1THRBHDAC1HDAC7HDAC8 | |
| SCHEMBL9501362 | 0.91 | DGAT1 (0.39) | DGAT1ALDH1A1 | |
| SCHEMBL11205420 | 0.91 | THRB (0.40) | DGAT1THRBHDAC1HDAC7HDAC8 | |
| SCHEMBL517251 | 0.91 | THRB (0.40) | DGAT1THRBHDAC1HDAC7HDAC8 | |
| SCHEMBL672362 | 0.91 | THRB (0.40) | DGAT1THRBHDAC1HDAC7HDAC8 | |
| SCHEMBL3082673 | 0.91 | THRB (0.40) | DGAT1THRBHDAC1HDAC7HDAC8 | |
| SCHEMBL497763 | 0.88 | DGAT1 (0.39) | DGAT1THRBHDAC1HDAC7HDAC8 | |
| SCHEMBL497426 | 0.84 | THRB (0.52) | DGAT1THRBHDAC1HDAC7HDAC8 | |
| SCHEMBL517150 | 0.84 | THRB (0.52) | DGAT1THRBHDAC1HDAC7HDAC8 | |
| SCHEMBL516962 | 0.84 | THRB (0.52) | DGAT1THRBHDAC1HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106222-B2 | Fluorine-containing ether compound | FUJIFILM CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20090018350-A1 | NOVEL FLUORINE-CONTAINING ETHER COMPOUND | FUJIFILM CORPORATION (JP) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018350-A1 | NOVEL FLUORINE-CONTAINING ETHER COMPOUND | AFF4, AFF1, AFF2 | DGAT1 605/4885THRB 2210/4885HDAC1 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.