Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2905880 | 0.99 | POLB (0.42) | POLBSMN1; SMN2LMNAHIF1AEPAS1 | |
| Hydrochloric Acid SCHEMBL2912613 | 0.90 | ALDH1A1 (0.37) | POLBSMN1; SMN2LMNAHIF1AEPAS1 | |
| SCHEMBL2911151 | 0.82 | KMT2A (0.34) | POLBSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL4969907 | 0.82 | HTT (0.40) | SMN1; SMN2LMNAL3MBTL1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL2914481 | 0.80 | LMNA (0.45) | POLBSMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL2913560 | 0.79 | GAA (0.38) | LMNAL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL27616609 | 0.79 | CA12 (0.34) | LMNAL3MBTL1ALDH1A1GAAKDM4E | |
| SCHEMBL2909609 | 0.79 | SMN1; SMN2 (0.32) | POLBSMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL2912943 | 0.78 | PKM (0.49) | POLBSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL2910924 | 0.78 | KDM1A (0.40) | LMNAHIF1AL3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408036-B1 | PROCESS FOR PRODUCING BENZOFURAN DERIVATIVE | TAKEDA PHARMACEUTICAL (JP) | 2008-08-27 | — | — | EP | disclosed |
| US-7323577-B2 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20060142598-A1 | Process for producing benzofuran derivative | TAWADA HIROYUKI | 2006-06-29 | — | — | US | disclosed |
| US-7034166-B2 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |
| US-20040210066-A1 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-10-21 | — | — | US | disclosed |
| EP-1408036-A1 | PROCESS FOR PRODUCING BENZOFURAN DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210066-A1 | Process for producing benzofuran derivative | IWS1, HAT1, BRD1 | POLB 1656/4885SMN1; SMN2 3784/4885LMNA 2920/4885 |
| US-20060142598-A1 | Process for producing benzofuran derivative | AHR, CBR3, HAT1 | POLB 1921/4885SMN1; SMN2 3801/4885LMNA 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.