Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912430 | 0.89 | NPBWR1 (0.36) | SMN1; SMN2IDO1ABCB1ALDH1A1MAPT | |
| SCHEMBL2911151 | 0.89 | KMT2A (0.34) | HTTSMN1; SMN2HPGDALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2910240 | 0.88 | NPBWR1 (0.36) | SMN1; SMN2IDO1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2905966 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1LMNAMAPTCA12 | |
| SCHEMBL2909609 | 0.85 | SMN1; SMN2 (0.32) | HTTSMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL4969221 | 0.82 | POLB (0.43) | HTTSMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL3600851 | 0.81 | HTT (0.40) | HTTSMN1; SMN2IDO1NPSR1HPGD | |
| Hydrochloric Acid SCHEMBL2905880 | 0.81 | POLB (0.42) | HTTSMN1; SMN2HPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2914481 | 0.80 | LMNA (0.45) | HTTSMN1; SMN2NPSR1HPGDKDM4E | |
| SCHEMBL2911751 | 0.79 | RAB9A (0.36) | SMN1; SMN2KDM4EALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408036-B1 | PROCESS FOR PRODUCING BENZOFURAN DERIVATIVE | TAKEDA PHARMACEUTICAL (JP) | 2008-08-27 | — | — | EP | claimed |
| US-7323577-B2 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-29 | — | — | US | claimed |
| US-20060142598-A1 | Process for producing benzofuran derivative | TAWADA HIROYUKI | 2006-06-29 | — | — | US | claimed |
| US-20040210066-A1 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-10-21 | — | — | US | claimed |
| EP-1408036-A1 | PROCESS FOR PRODUCING BENZOFURAN DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 2004-04-14 | — | — | EP | claimed |
| EP-1408036-B1 | PROCESS FOR PRODUCING BENZOFURAN DERIVATIVE | TAKEDA PHARMACEUTICAL (JP) | 2008-08-27 | — | — | EP | disclosed |
| US-7323577-B2 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20060142598-A1 | Process for producing benzofuran derivative | TAWADA HIROYUKI | 2006-06-29 | — | — | US | disclosed |
| US-7034166-B2 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |
| US-20040210066-A1 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-10-21 | — | — | US | disclosed |
| EP-1408036-A1 | PROCESS FOR PRODUCING BENZOFURAN DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210066-A1 | Process for producing benzofuran derivative | IWS1, HAT1, BRD1 | HTT 1464/4885SMN1; SMN2 3784/4885IDO1 1230/4885 |
| US-20060142598-A1 | Process for producing benzofuran derivative | AHR, CBR3, HAT1 | HTT 1140/4885SMN1; SMN2 3801/4885IDO1 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.