Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.76 |
| ▸ | NSD2 | O96028 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28239389 | 0.88 | EGLN1 (0.60) | EGLN1NSD2MAPTMAPK8ATM | |
| SCHEMBL2200760 | 0.86 | EGLN1 (1.00) | EGLN1NSD2MAPTMAPK8ATM | |
| SCHEMBL18641961 | 0.85 | EGLN1 (0.57) | EGLN1NSD2MAPTKMT2AMEN1 | |
| SCHEMBL15447128 | 0.85 | EGLN1 (0.57) | EGLN1NSD2MAPTKMT2AMEN1 | |
| SCHEMBL12186787 | 0.85 | HDAC6 (0.68) | EGLN1 | |
| SCHEMBL29617730 | 0.85 | EGLN1 (0.57) | EGLN1NSD2MAPTKMT2AMEN1 | |
| SCHEMBL4969813 | 0.84 | ALDH1A1 (0.64) | EGLN1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2144302 | 0.83 | EGLN1 (0.75) | EGLN1NSD2MAPTMAPK8ATM | |
| SCHEMBL7382937 | 0.82 | EGLN1 (0.74) | EGLN1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL3182140 | 0.81 | NSD2 (0.68) | EGLN1NSD2MAPTMAPK8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |