Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923923 | 0.82 | PTGES (0.48) | INSRIGF1RCYP1A2CYP2A6PYCR1 | |
| SCHEMBL9365569 | 0.79 | CYP1A2 (0.50) | INSRIGF1RCYP1A2CYP2A6PYCR1 | |
| SCHEMBL8089793 | 0.78 | CYP1A2 (0.54) | INSRIGF1RCYP1A2CYP2A6PYCR1 | |
| SCHEMBL17447228 | 0.78 | PYCR1 (0.61) | CYP1A2CYP2A6PYCR1SLC6A2SLC6A4 | |
| SCHEMBL6675829 | 0.77 | BCHE (0.59) | CYP1A2CYP2A6PYCR1SLC6A2SLC6A4 | |
| SCHEMBL29764499 | 0.77 | BCHE (0.59) | CYP1A2CYP2A6PYCR1SLC6A2SLC6A4 | |
| SCHEMBL6566946 | 0.76 | BCHE (0.55) | CYP1A2CYP2A6PYCR1SIGMAR1HDAC3 | |
| SCHEMBL20022001 | 0.75 | CYP1A2 (0.61) | CYP1A2CYP2A6PYCR1SLC6A2SLC6A4 | |
| SCHEMBL2442113 | 0.75 | CYP1A2 (0.56) | CYP1A2PTGESALOX5MC4RMC3R | |
| SCHEMBL8088882 | 0.75 | SLC6A2 (0.56) | CYP1A2CYP2A6PYCR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080315155-A1 | Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-10-23 | — | — | US | disclosed |
| EP-1966265-A2 | BLENDS OF DIAMINES HAVING REDUCED COLOR | Albermarle Corporation (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1966122-A1 | DIAMINES HAVING REDUCED COLOR | Albermarle Corporation (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007079365-A2 | BLENDS OF DIAMINES HAVING REDUCED COLOR | ALBEMARLE CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007079367-A1 | DIAMINES HAVING REDUCED COLOR | ALBEMARLE CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | DDT, DDC, AOC1 | INSR 3051/4885IGF1R 4591/4885CYP1A2 524/4885 |
| US-20080315155-A1 | Diamines Having Reduced Color | DDT, DPYD, DDC | INSR 4560/4885IGF1R 4885/4885CYP1A2 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.