SCHEMBL497118

SCHEMBL497118

CC(C)CNC(=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.54
KMT2A Q03164 2/20 0.54
HSD17B10 Q99714 1/20 0.54
HPGD P15428 2/20 0.49
MLYCD O95822 1/20 0.49
LMNA P02545 2/20 0.47
RECQL P46063 1/20 0.47
KDM4E B2RXH2 2/20 0.46
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MAOB P27338 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALOX5 P09917 2/20 0.42
PTGS1 P23219 2/20 0.42
PTGS2 P35354 2/20 0.42
CNR2 P34972 1/20 0.41
HMGCR P04035 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608126 0.88 LMNA (0.45) GAAKMT2AHSD17B10LMNARECQL
SCHEMBL5063742 0.83 GAA (0.58) GAAKMT2AHSD17B10HPGDMLYCD
SCHEMBL11437810 0.83 MAOB (0.53) GAAKMT2ALMNARECQLMAOB
SCHEMBL11632170 0.81 PTGS1 (0.56) GAAKMT2ALMNARECQLNPSR1
SCHEMBL2908793 0.80 HSD17B10 (0.78) GAAKMT2AHSD17B10HPGDMLYCD
SCHEMBL18748508 0.80 GAA (0.62) GAAKMT2AHSD17B10HPGDMLYCD
SCHEMBL8607170 0.80 CYP1A2 (0.41) GAAKMT2AHSD17B10LMNARECQL
SCHEMBL20206991 0.80 GAA (0.61) GAAKMT2AHSD17B10HPGDMLYCD
SCHEMBL16610341 0.79 MLYCD (0.51) GAAKMT2AHSD17B10HPGDMLYCD
SCHEMBL5058222 0.79 NR5A2 (0.65) GAAKMT2AHSD17B10HPGDMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3387010-A1 COMPOSITIONS AND METHODS FOR EXPRESSION OF MULTIPLE BIOLOGICALLY ACTIVE POLYPEPTIDES FROM A SINGLE VECTOR FOR TREATMENT OF CARDIAC CONDITIONS AND OTHER PATHOLOGIES Intrexon Corporation (US) 2018-10-17 EP claimed
WO-2017083750-A1 COMPOSITIONS AND METHODS FOR EXPRESSION OF MULTIPLE BIOLOGICALLY ACTIVE POLYPEPTIDES FROM A SINGLE VECTOR FOR TREATMENT OF CARDIAC CONDITIONS AND OTHER PATHOLOGIES INTREXON CORPORATION (US) 2017-05-18 WO claimed
US-20060240088-A1 Caged ligands and uses thereof ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2006-10-26 US claimed
US-7045315-B2 Methods for modulating expression of exogenous genes in mammalian systems THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2006-05-16 US claimed
WO-2004037983-A2 CAGED LIGANDS AND USES THEREOF ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2004-05-06 WO claimed
US-6723531-B2 DNA CONSTRUCT COMPRISING SAID EXOGENOUS GENE UNDER THE CONTROL OF AN ECDYSONE RESPONSE ELEMENT; AND A MODIFIED ECDYSONE RECEPTOR WHICH, IN THE PRESENCE OF A LIGAND THEREFOR, BINDS TO SAID ECDYSONE RESPONSE ELEMENT THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2004-04-20 US claimed
US-20020187972-A1 Methods for modulating expression of exogenous genes in mammalian systems THE SALK INSTITUTE OF BIOLOGICAL STUDIES 2002-12-12 US claimed
US-20020177564-A1 METHOD FOR MODULATING EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS, AND PRODUCTS RELATED THERETO HOWARD HUGHES MEDICAL INSTITUTE 2002-11-28 US claimed
US-6333318-B1 USED IN THERAPY; FOR DELIVERING RECOMBINANT PROTEINS INTO A VARIETY OF CELLS WITHIN A PATIENT THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2001-12-25 US claimed
US-20260098063-A1 HUMAN PAPILLOMAVIRUS VACCINES AND USES OF THE SAME PRECIGEN INC (US) 2026-04-09 US disclosed
EP-4716690-A2 NOVEL ADENOVIRUS VACCINE THERAPY FOR THE TREATMENT OF RECURRENT RESPIRATORY PAPILLOMATOSIS Precigen, Inc. (US) 2026-04-01 EP disclosed
EP-4716689-A2 HUMAN PAPILLOMAVIRUS VACCINES AND USES OF THE SAME Precigen, Inc. (US) 2026-04-01 EP disclosed
US-20260035432-A1 ROR-1 SPECIFIC CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF PRECIGEN, INC. (US) 2026-02-05 US disclosed
US-20250325665-A1 FUSION CONSTRUCTS AND METHODS OF USING THEREOF PRECIGEN, INC. (US) 2025-10-23 US disclosed
US-20020119521-A1 Novel ecdysone receptor-based inducible gene expression system RHEOGENE, INC. (DE CORPORATION) 2002-08-29 US disclosed
WO-2002066613-A2 NOVEL ECDYSONE RECEPTOR/INVERTEBRATE RETINOID X RECEPTOR-BASED INDUCIBLE GENE EXPRESSION SYSTEM RHEOGENE HOLDINGS, INC (US) 2002-08-29 WO disclosed
WO-2002066614-A2 CHIMERIC RETINOID X RECEPTORS AND THEIR USE IN A NOVEL ECDYSONE RECEPTOR-BASED INDUCIBLE GENE EXPRESSION SYSTEM RHEOGENE HOLDINGS, INC. (US) 2002-08-29 WO disclosed
US-20020110861-A1 Multiple inducible gene regulation system RHEOGENE, INC. 2002-08-15 US disclosed
WO-2002029075-A2 MULTIPLE INDUCIBLE GENE REGULATION SYSTEM ROHM AND HAAS COMPANY (US) 2002-04-11 WO disclosed
US-6333318-B1 USED IN THERAPY; FOR DELIVERING RECOMBINANT PROTEINS INTO A VARIETY OF CELLS WITHIN A PATIENT THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2001-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020187972-A1 Methods for modulating expression of exogenous genes in mammalian systems NR2E3, GFRA2, GFRA3 GAA 3740/4885KMT2A 1788/4885HSD17B10 797/4885
US-20260035432-A1 ROR-1 SPECIFIC CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF RORB, ICOS, RORC GAA 2880/4885KMT2A 1078/4885HSD17B10 4055/4885
US-20260098063-A1 HUMAN PAPILLOMAVIRUS VACCINES AND USES OF THE SAME ANKRD54, POTEE, ANKK1 GAA 4787/4885KMT2A 3819/4885HSD17B10 4846/4885
US-20020110861-A1 Multiple inducible gene regulation system MYCBP, MYC, STAT3 GAA 2541/4885KMT2A 1444/4885HSD17B10 1264/4885
US-20250325665-A1 FUSION CONSTRUCTS AND METHODS OF USING THEREOF MUC1, CD40, TNFRSF1A GAA 1000/4885KMT2A 3160/4885HSD17B10 4782/4885
US-20020177564-A1 METHOD FOR MODULATING EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS, AND PRODUCTS RELATED THERETO OR51E2, HAVCR2, NGFR GAA 2851/4885KMT2A 2440/4885HSD17B10 1764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.