Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709959 | 0.91 | PDE3A (0.41) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL22363161 | 0.89 | POLA1 (0.42) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL8627861 | 0.85 | PDE3A (0.44) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL29720484 | 0.84 | CYP3A4 (0.35) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL6394687 | 0.83 | RNASE1 (0.32) | POLBABL1RIN1ALDH1A1ADRB1 | |
| SCHEMBL1763155 | 0.82 | PDE3A (0.42) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL30305979 | 0.81 | PDE4D (0.33) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL598527 | 0.80 | ABL1 (0.40) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL5201335 | 0.80 | TYMP (0.42) | ST6GAL1 | |
| SCHEMBL10344618 | 0.80 | DNMT1 (0.33) | PDE3APDE4DSLC29A1POLBDNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114652836-A | T3SS small-molecule inhibitor and screening method and application thereof | 山东大学 | 2022-06-24 | — | — | CN | claimed |
| WO-2000075154-A2 | PROTECTED NUCLEOSIDES | ALLIEDSIGNAL INC. (US) | 2000-12-14 | — | — | WO | claimed |
| US-12559517-B2 | Oligonucleotide manufacturing method | AJINOMOTO CO., INC. (JP) | 2026-02-24 | — | — | US | disclosed |
| US-20260028368-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | INTEGRATED DNA TECH INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12459968-B2 | Oligonucleotide synthesis on solid support | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| CN-118005706-A | Preparation method of 2',3' -dideoxynucleotide | 天津奥利芙生物技术有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-115721633-B | Application of hydroxy alizarin as T3SS small molecule inhibitor | 山东大学 | 2024-05-03 | — | — | CN | disclosed |
| EP-4299736-A2 | HYDROLASES AND USES THEREOF | Vilnius University (LT) | 2024-01-03 | — | — | EP | disclosed |
| CN-112533892-B | Alkoxyphenyl derivative, nucleoside protector, nucleotide protector, method for producing oligonucleotide, and method for removing substituent | 藤本化学制品株式会社 | 2023-09-08 | — | — | CN | disclosed |
| US-20230119227-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | INTEGRATED DNA TECHNOLOGIES, INC. | 2023-04-20 | — | — | US | disclosed |
| CN-115721633-A | Application of hydroxyalizarin as T3SS small-molecule inhibitor | 山东大学 | 2023-03-03 | — | — | CN | disclosed |
| WO-1992013869-A1 | METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM | GILEAD SCIENCES, INC. (US) | 1992-08-20 | — | — | WO | disclosed |
| EP-0135587-B1 | DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS | SYNGENE, INC. (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0155950-B1 | OLIGONUCLEOTIDE POLYMERIC SUPPORT SYSTEM | MOLECULAR BIOSYSTEMS INC (US) | 1990-01-17 | — | — | EP | disclosed |
| EP-0270651-A4 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0270651-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988000201-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) | 1988-01-14 | — | — | WO | disclosed |
| EP-0191869-A1 | FISH CALCITONIN DERIVATIVE, PROCESS FOR ITS PREPARATION, AND GENE SYSTEM THEREFOR | HODOGAYA CHEMICAL COMPANY, LIMITED (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0115613-A2 | DNA sequences, their preparation, plasmids containing these sequences and their use in the synthesis of eukaryotic gene products in prokaryotes | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1984-08-15 | — | — | EP | disclosed |
| EP-0058954-A2 | Tridecadeoxynucleotide, process for its preparation and the application | Dr. Karl Thomae GmbH (DE) | 1982-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028368-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | NSUN2, RNGTT, POLR2H | PDE3A 4766/4885PDE4D 4860/4885SLC29A1 405/4885 |
| US-12459968-B2 | Oligonucleotide synthesis on solid support | RNGTT, SSU72, NSUN2 | PDE3A 4799/4885PDE4D 4408/4885SLC29A1 229/4885 |
| US-12559517-B2 | Oligonucleotide manufacturing method | POLL, IGF2BP1, POLI | PDE3A 3104/4885PDE4D 2640/4885SLC29A1 1338/4885 |
| US-20230119227-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | RNGTT, SSU72, NSUN2 | PDE3A 4799/4885PDE4D 4408/4885SLC29A1 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.