Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | BCHE | P06276 | 5/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970261 | 0.82 | KDM4E (0.42) | KMT2AMEN1ACHEBCHEGRIN1 | |
| SCHEMBL4970199 | 0.81 | CYP11B1 (0.37) | HTR6HTR1AHTR2AHTR7KMT2A | |
| SCHEMBL4969052 | 0.81 | HTR6 (0.49) | HTR6HTR1AHTR2AHTR7KMT2A | |
| SCHEMBL4970714 | 0.80 | MEN1 (0.40) | HTR6KMT2AMEN1ACHEMAPT | |
| SCHEMBL4968898 | 0.80 | MEN1 (0.44) | HTR6HTR1AHTR2AHTR7KMT2A | |
| SCHEMBL4972772 | 0.80 | HTR6 (0.39) | HTR6KMT2AACHEBCHEGRIN1 | |
| SCHEMBL4970496 | 0.79 | HTR6 (0.40) | HTR6HTR1AHTR2AHTR7KMT2A | |
| SCHEMBL4967820 | 0.77 | HTR6 (0.43) | HTR6HTR1AHTR2AHTR7KMT2A | |
| SCHEMBL4972774 | 0.76 | MEN1 (0.41) | HTR6HTR1AHTR2AHTR7KMT2A | |
| SCHEMBL4971672 | 0.76 | HTR6 (0.43) | HTR6HTR1AHTR2AHTR7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654228-B1 | TETRAHYDROCARBAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM CORP (US) | 2008-10-22 | — | — | EP | claimed |