Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 6/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.32 |
| ▸ | MC5R | P33032 | 2/20 | 0.31 |
| ▸ | MC3R | P41968 | 2/20 | 0.31 |
| ▸ | MC1R | Q01726 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970054 | 0.88 | REN (0.36) | RENKDM4E | |
| SCHEMBL4970765 | 0.85 | USP30 (0.35) | RENMC4RSLC6A4 | |
| SCHEMBL3615232 | 0.82 | REN (0.45) | REN | |
| SCHEMBL3615227 | 0.82 | REN (0.45) | REN | |
| SCHEMBL3615228 | 0.82 | REN (0.45) | REN | |
| SCHEMBL4973471 | 0.81 | REN (0.43) | RENKDM4E | |
| SCHEMBL4973950 | 0.79 | REN (0.45) | RENKDM4E | |
| SCHEMBL4969812 | 0.79 | REN (0.45) | RENKDM4E | |
| SCHEMBL3881752 | 0.78 | REN (0.52) | RENKDM4E | |
| SCHEMBL3965737 | 0.78 | REN (0.36) | RENKDM4EMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |