Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971676 | 0.85 | REN (0.37) | RENMC4RSLC6A4 | |
| SCHEMBL3609954 | 0.82 | MEN1 (0.44) | USP30REN | |
| SCHEMBL3609953 | 0.82 | MEN1 (0.44) | USP30REN | |
| SCHEMBL3609955 | 0.82 | MEN1 (0.44) | USP30REN | |
| SCHEMBL4970274 | 0.82 | REN (0.40) | USP30REN | |
| SCHEMBL4971174 | 0.77 | SLC6A3 (0.36) | USP30RENSLC6A4 | |
| SCHEMBL3965737 | 0.73 | REN (0.36) | RENMC4R | |
| SCHEMBL4970054 | 0.73 | REN (0.36) | REN | |
| SCHEMBL3615228 | 0.68 | REN (0.45) | USP30REN | |
| SCHEMBL3615232 | 0.68 | REN (0.45) | USP30REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |