Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15825704 | 0.83 | — | — | |
| SCHEMBL5801362 | 0.81 | HTR3E (0.37) | SIGMAR1L3MBTL3L3MBTL1KDM1AIRAK4 | |
| SCHEMBL30791081 | 0.81 | L3MBTL3 (0.41) | SIGMAR1L3MBTL3L3MBTL1KDM1AMAOB | |
| SCHEMBL26101147 | 0.76 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL27568268 | 0.76 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL28752476 | 0.75 | SMYD3 (0.34) | SIGMAR1 | |
| SCHEMBL28752475 | 0.75 | SMYD3 (0.34) | SIGMAR1 | |
| SCHEMBL5800638 | 0.73 | GAA (0.40) | SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL28757061 | 0.73 | SIGMAR1 (0.36) | SIGMAR1JAK1 | |
| SCHEMBL19988061 | 0.72 | ALDH1A1 (0.35) | SIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973917-A2 | PROTEIN KINASE INHIBITORS | Abbott Laboratories (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007079164-A2 | PROTEIN KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2007-07-12 | — | — | WO | disclosed |