SCHEMBL49730

SCHEMBL49730

CCCCO[N]c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 2/20 0.47
▸ CYP1A2 P05177 2/20 0.41
▸ CYP2C9 P11712 2/20 0.41
▸ CYP2C19 P33261 2/20 0.41
▸ ESR1 P03372 1/20 0.41
▸ TSHR P16473 3/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ ALDH1A1 P00352 3/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ CHRNA7 P36544 1/20 0.37
▸ CHRNA10 Q9GZZ6 1/20 0.37
▸ CHRNA9 Q9UGM1 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ PPARG P37231 1/20 0.36
▸ PPARA Q07869 1/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ CYP19A1 P11511 1/20 0.36
▸ HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6001526 0.87 LMNA (0.39) LTA4HALDH1A1CHRNA7CHRNA10CHRNA9
SCHEMBL49789 0.78 ALDH1A1 (0.39) LTA4HTDP1L3MBTL1ALDH1A1MAPK1
SCHEMBL5830120 0.74 ALDH1A1 (0.36) ALDH1A1
SCHEMBL3183185 0.74 TAAR1 (0.46) LTA4HCYP1A2TSHRTDP1ALDH1A1
SCHEMBL6774703 0.73 MMP2 (0.37) PPARA
SCHEMBL11836140 0.73 LTA4H (0.43) LTA4HESR1TSHRALDH1A1CYP3A4
SCHEMBL4942739 0.73 LTA4H (0.43) LTA4HESR1TSHRALDH1A1CYP3A4
SCHEMBL28330356 0.72 CHRNA7 (0.66) LTA4HCYP1A2CYP2C9CYP2C19ESR1
SCHEMBL11693379 0.72 CHRNA7 (0.66) LTA4HCYP1A2CYP2C9CYP2C19ESR1
SCHEMBL17215464 0.71 LTA4H (0.47) LTA4HCYP1A2CYP2C9CYP2C19ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6713146-B2 SINGLY RECORDABLE COMPACT DISC (CD-R) BAYER AKTIENGESELLSCHAFT (DE) 2004-03-30 — — US claimed
EP-1322906-A1 OPTICAL DATA STORAGE DEVICE CONTAINING A CO-PHTHALOCYANIN COMPLEX IN THE OPTICALLY WRITABLE INFORMATION LAYER Bayer Aktiengesellschaft (DE) 2003-07-02 — — EP claimed
EP-1292579-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE Pharmacia Corporation (US) 2003-03-19 — — EP claimed
US-20020127366-A1 Optical data stores containing a Co-phthalocyanine complex in the information layer recordable using light LANXESS DEUTSCHLAND GMBH (DE) 2002-09-12 — — US claimed
WO-2002025205-A1 OPTICAL DATA STORAGE DEVICE CONTAINING A CO-PHTHALOCYANIN COMPLEX IN THE OPTICALLY WRITABLE INFORMATION LAYER BAYER AKTIENGESELLSCHAFT (DE) 2002-03-28 — — WO claimed
WO-2001087854-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE PHARMACIA CORPORATION (US) 2001-11-22 — — WO claimed
WO-2001087851-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIMIDINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE PHARMACIA CORPORATION (US) 2001-11-22 — — WO claimed
EP-2526138-B1 NOVEL REAGENTS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN II LTD (GB) 2024-02-28 — — EP disclosed
EP-3981819-B1 NOVEL REAGENTS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN II LTD (GB) 2024-02-28 — — EP disclosed
EP-4322238-A2 NOVEL REAGENTS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION Sirigen II Limited (GB) 2024-02-14 — — EP disclosed
US-11899018-B2 Reagents for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2024-02-13 — — US disclosed
US-11874278-B2 Reagents for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2024-01-16 — — US disclosed
US-20230273215-A1 Novel Reagents for Directed Biomarker Signal Amplification SIRIGEN, INC. 2023-08-31 — — US disclosed
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 — — EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 — — US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 — — US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 — — EP disclosed
EP-0183191-B1 THIENYLTHIAZOLE COMPOUNDS Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1989-05-10 — — EP disclosed
US-4720493-A Thienylthiazole compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1988-01-19 — — US disclosed
EP-0183191-A1 Thienylthiazole compounds Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1986-06-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11874278-B2 Reagents for directed biomarker signal amplification RNGTT, CAPG, CA14 LTA4H 2158/4885CYP1A2 4879/4885CYP2C9 4865/4885
US-20230273215-A1 Novel Reagents for Directed Biomarker Signal Amplification RNGTT, CAPG, CD2BP2 LTA4H 2260/4885CYP1A2 4883/4885CYP2C9 4878/4885
US-11899018-B2 Reagents for directed biomarker signal amplification RNGTT, CAPG, CA14 LTA4H 2158/4885CYP1A2 4879/4885CYP2C9 4865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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