Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 3/20 | 0.31 |
| ▸ | BLM | P54132 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10024649 | 1.00 | DNM1 (0.36) | DNM1RAD52MAPTRAB9ANPSR1 | |
| SCHEMBL10024646 | 0.89 | DNM1 (0.51) | DNM1MAPTRAB9ANPSR1LMNA | |
| SCHEMBL10024643 | 0.89 | MAPT (0.43) | DNM1MAPTRAB9ANPSR1LMNA | |
| SCHEMBL496950 | 0.89 | DNM1 (0.51) | DNM1MAPTRAB9ANPSR1LMNA | |
| SCHEMBL15068279 | 0.87 | DNM1 (0.39) | DNM1 | |
| SCHEMBL497179 | 0.87 | MAPT (0.36) | DNM1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL10024644 | 0.83 | MAPT (0.37) | RAD52MAPTRAB9ANPSR1LMNA | |
| SCHEMBL496883 | 0.81 | JAK2 (0.33) | DNM1JAK2 | |
| SCHEMBL496885 | 0.81 | JAK2 (0.33) | DNM1JAK2 | |
| SCHEMBL497045 | 0.79 | CYP1A2 (0.30) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2579841-B1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | ORÉAL L (FR) | 2016-09-14 | — | — | EP | disclosed |
| US-8771376-B2 | Composition comprising at least one 2-pyrrolidone functionalized with an ester or amide radical, and at least one pigment or direct dye, for dyeing keratin materials | L'OREAL (FR) | 2014-07-08 | — | — | US | disclosed |
| EP-2231607-B1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-AMINO-3-HYDROXYPYRIDINE, AND HAIR DYEING PROCESS USING THESE DYES AND PRECURSORS | OREAL (FR) | 2013-07-03 | — | — | EP | disclosed |
| US-20130152314-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | L'OREAL (FR) | 2013-06-20 | — | — | US | disclosed |
| EP-2579841-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | L'Oréal (FR) | 2013-04-17 | — | — | EP | disclosed |
| US-8105394-B2 | Azomethine direct dyes or reduced precursors of azomethine direct dyes obtained from 2-alkylresorcinols, and hair dyeing process using these dyes or precursors | L'OREAL S.A. (FR) | 2012-01-31 | — | — | US | disclosed |
| WO-2011154458-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | L'OREAL (FR) | 2011-12-15 | — | — | WO | disclosed |
| US-20110041262-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF AZOMETHINE DIRECT DYES OBTAINED FROM 2-ALKYLRESORCINOLS, AND HAIR DYEING PROCESS USING THESE DYES OR PRECURSORS | L'OREAL S.A (FR) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130152314-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | KRT18, ADH1A, ADH5 | DNM1 1690/4885RAD52 615/4885MAPT 254/4885 |
| US-20110041262-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF AZOMETHINE DIRECT DYES OBTAINED FROM 2-ALKYLRESORCINOLS, AND HAIR DYEING PROCESS USING THESE DYES OR PRECURSORS | KRT18, AKR1C4, QDPR | DNM1 2971/4885RAD52 134/4885MAPT 1558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.