SCHEMBL4976286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1396719	0.90	TRPV1 (0.48)	TRPV1PDPK1MET
	SCHEMBL4975287	0.89	PDPK1 (0.39)	TRPV1PDPK1METEGFRPDGFRB
	SCHEMBL4974501	0.88	TRPV1 (0.37)	TRPV1PDPK1METEGFRPDGFRB
	SCHEMBL4977676	0.84	HSD11B1 (0.40)	PDPK1MET
	SCHEMBL4969657	0.83	CIT (0.41)	PDPK1METCITFLT3
	SCHEMBL4975481	0.82	PDPK1 (0.37)	PDPK1METCIT
	SCHEMBL4971833	0.81	MET (0.45)	PDPK1METKDR
	SCHEMBL4972499	0.81	MET (0.42)	PDPK1MET
	SCHEMBL4971839	0.81	RAB9A (0.45)	TRPV1METKDR
	SCHEMBL4973857	0.81	TP53 (0.42)	MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.