Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MITF | O75030 | 2/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
| ▸ | RHOA | P61586 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430904 | 0.93 | AKR1C3 (0.58) | AKR1C3ALDH1A1NR1H4NPC1RAB9A | |
| Phenol SCHEMBL27737069 | 0.92 | AKR1C3 (0.60) | AKR1C3ALDH1A1NR1H4NPC1RAB9A | |
| Isophthalic Acid SCHEMBL27361534 | 0.91 | AKR1C3 (0.58) | AKR1C3ALDH1A1NR1H4NPC1RAB9A | |
| SCHEMBL873032 | 0.86 | AKR1C3 (0.61) | AKR1C3ALDH1A1NR1H4NPC1RAB9A | |
| SCHEMBL8285571 | 0.85 | KMT2A (0.59) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8294937 | 0.84 | MEN1 (0.57) | MEN1KMT2A | |
| SCHEMBL25717164 | 0.83 | AKR1C3 (0.72) | AKR1C3NPC1RAB9AMITFMEN1 | |
| SCHEMBL6325442 | 0.83 | AKR1C3 (0.58) | AKR1C3NR1H4SMN1; SMN2GAAHPGD | |
| Isophthalic Acid SCHEMBL27820333 | 0.82 | RXRA (0.51) | AKR1C3ALDH1A1NR1H4NPC1RAB9A | |
| SCHEMBL9782100 | 0.82 | AKR1C3 (0.61) | AKR1C3ALDH1A1NR1H4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | claimed |
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | disclosed |
| US-10604492-B2 | CFTR regulators and methods of use thereof | THE REGENTS OF THE UNIVERSTIY OF CALIFORNIA (US) | 2020-03-31 | — | — | US | disclosed |
| CN-106431990-B | Preparation method of N- (4-ethoxycarbonylphenyl) -N '-methyl-N' -phenylformamidine | 中昊(大连)化工研究设计院有限公司 | 2018-09-07 | — | — | CN | disclosed |
| WO-2017196261-A1 | JAK AND HDAC DUAL-INHIBITOR COMPOUNDS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-11-16 | — | — | WO | disclosed |
| US-20170320818-A1 | SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | UNIV DREXEL (US) | 2017-11-09 | — | — | US | disclosed |
| US-9399619-B2 | Sulfamoylbenzamide derivatives as antiviral agents against HBV infection | BARUCH S. BLUMBERG INSTITUTE (US) | 2016-07-26 | — | — | US | disclosed |
| CN-103703114-B | There is the lubricating composition improving tbn retention | THE LUBRIZOL CORP. (US) | 2016-02-10 | — | — | CN | disclosed |
| US-9222051-B2 | Lubricating composition with improved TBN retention | THE LUBRIZOL CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| CN-103210069-B | Aminobenzoic acid derivatives | THE LUBRIZOL CORP. (US) | 2015-11-25 | — | — | CN | disclosed |
| WO-1996004242-A1 | ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |
| US-5466268-A | Polyalkyl and polyalkenyl aromatic amides and fuel compositions containing the same | CHEVRON CHEMICAL COMPANY (US) | 1995-11-14 | — | — | US | disclosed |
| US-5407452-A | Antideposit agents | CHEVRON CHEMICAL COMPANY (US) | 1995-04-18 | — | — | US | disclosed |
| US-5380345-A | Fuel additives | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1995-01-10 | — | — | US | disclosed |
| US-5276148-A | Phenylazobenzenes or naphthylazobenzenes having a plurality of fiber-reactive groups | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |
| US-4528136-A | Process for preparing 2-[bis(aryl)methyl]benzoic acids | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-07-09 | — | — | US | disclosed |
| US-4399291-A | CONDENSATION OF A BENZALDEHYDE, AN ANILINE, AN AMINOBENZOIC ACID; OXIDATION | STERLING DRUG INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0082394-A2 | A process for the production of aminophthalides and amino benzoic acids | STERLING DRUG INC. (US) | 1983-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604492-B2 | CFTR regulators and methods of use thereof | CFTR, SLC26A4, CLCN2 | AKR1C3 1984/4885ALDH1A1 2135/4885NR1H4 186/4885 |
| US-20170320818-A1 | SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | ALKBH5, SULT1A1, SHMT1 | AKR1C3 2414/4885ALDH1A1 2034/4885NR1H4 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.