Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.64 |
| ▸ | EP300 | Q09472 | 1/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.59 |
| ▸ | FNTA | P49354 | 1/20 | 0.59 |
| ▸ | FNTB | P49356 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799610 | 0.89 | ALDH1A1 (0.64) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 | |
| SCHEMBL4799596 | 0.89 | ALDH1A1 (0.64) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 | |
| SCHEMBL4742813 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 | |
| SCHEMBL7726357 | 0.85 | NPC1 (0.72) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 | |
| SCHEMBL4393965 | 0.84 | KDM4E (0.81) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 | |
| SCHEMBL3106237 | 0.82 | RHOC (0.62) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 | |
| SCHEMBL3106245 | 0.82 | RHOC (0.62) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 | |
| SCHEMBL2442864 | 0.82 | HTT (0.54) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 | |
| SCHEMBL9282048 | 0.82 | KCNH2 (0.56) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 | |
| SCHEMBL9282043 | 0.82 | KCNH2 (0.56) | ALDH1A1HTTMAPK1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976829-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007070556-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | disclosed |