Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 1/20 | 0.62 |
| ▸ | RHOA | P61586 | 1/20 | 0.62 |
| ▸ | EP300 | Q09472 | 6/20 | 0.58 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106245 | 1.00 | RHOC (0.62) | RHOCRHOAEP300CREBBPHTT | |
| SCHEMBL4799610 | 0.87 | ALDH1A1 (0.64) | EP300CREBBPHTTCYP2C9CYP2C19 | |
| SCHEMBL4799596 | 0.87 | ALDH1A1 (0.64) | EP300CREBBPHTTCYP2C9CYP2C19 | |
| SCHEMBL2442864 | 0.86 | HTT (0.54) | RHOCRHOAEP300CREBBPHTT | |
| SCHEMBL38658435 | 0.85 | LMNA (0.61) | HTTCYP2C9CYP2C19L3MBTL1POLB | |
| SCHEMBL4742813 | 0.82 | ALDH1A1 (0.60) | HTTCYP2C9CYP2C19RAB9APOLB | |
| SCHEMBL16495812 | 0.82 | CYP2C9 (0.51) | RHOCRHOAEP300CREBBPHTT | |
| SCHEMBL4978089 | 0.82 | ALDH1A1 (0.67) | EP300CREBBPHTTCYP2C9CYP2C19 | |
| SCHEMBL7974108 | 0.82 | DPP4 (0.53) | EP300CREBBPHTTCYP2C9CYP2C19 | |
| SCHEMBL4096438 | 0.82 | HTT (0.67) | RHOCRHOAEP300CREBBPHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906516-B2 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20100256131-A1 | CARBONYL COMPOUNDS | TSAKLAKIDIS CHRISTOS | 2010-10-07 | — | — | US | disclosed |
| US-20080003214-A1 | Medicaments Comprising Carbonyl Compounds, And The Use Thereof | MERCK PATENT GMBH (DE) | 2008-01-03 | — | — | US | disclosed |
| US-20060183739-A1 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256131-A1 | CARBONYL COMPOUNDS | F2, F11, PDHX | RHOC 3122/4885RHOA 2693/4885EP300 1026/4885 |
| US-20080003214-A1 | Medicaments Comprising Carbonyl Compounds, And The Use Thereof | F2, PDHX, SDHB | RHOC 2392/4885RHOA 1393/4885EP300 1061/4885 |
| US-20060183739-A1 | Carbonyl compounds | F2, F11, PDHX | RHOC 3122/4885RHOA 2693/4885EP300 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.