Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RHOC | P08134 | 1/20 | 0.47 |
| ▸ | RHOA | P61586 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799610 | 0.87 | ALDH1A1 (0.64) | HTTCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL4799596 | 0.87 | ALDH1A1 (0.64) | HTTCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL3106237 | 0.86 | RHOC (0.62) | HTTCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL3106245 | 0.86 | RHOC (0.62) | HTTCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL38658435 | 0.85 | LMNA (0.61) | HTTCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL4742813 | 0.82 | ALDH1A1 (0.60) | HTTCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL4978089 | 0.82 | ALDH1A1 (0.67) | HTTCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL16495812 | 0.82 | CYP2C9 (0.51) | HTTCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL7974108 | 0.82 | DPP4 (0.53) | HTTCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL4096438 | 0.82 | HTT (0.67) | HTTCYP2C9CYP2C19ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367824-B1 | Anti-viral derivatives of pyrimidine | ABBVIE INC (US) | 2016-03-23 | — | — | EP | disclosed |
| US-9163017-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-8541424-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2013-09-24 | — | — | US | disclosed |
| EP-2367824-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010075376-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2010-07-01 | — | — | WO | disclosed |
| US-20100168138-A1 | Anti-Viral Compounds | ABBOTT LABORATORIES (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168138-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | HTT 1821/4885CYP2C9 3780/4885CYP2C19 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.