Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4981471 | 0.93 | ALDH1A1 (0.64) | ALDH1A1KDM4ETDP1P2RX7EPHX2 | |
| SCHEMBL4979809 | 0.81 | LMNA (0.56) | ALDH1A1EPHX2SSTR4DRD4SIGMAR1 | |
| SCHEMBL4979388 | 0.81 | P2RX7 (0.54) | ALDH1A1P2RX7SSTR4DRD4SIGMAR1 | |
| SCHEMBL4982989 | 0.81 | NPC1 (0.57) | ALDH1A1P2RX7EPHX2SSTR4DRD4 | |
| SCHEMBL4982809 | 0.80 | DRD4 (0.49) | ALDH1A1P2RX7EPHX2SSTR4DRD4 | |
| SCHEMBL14263103 | 0.80 | P2RX7 (0.56) | ALDH1A1P2RX7SSTR4DRD4SSTR1 | |
| SCHEMBL4982031 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EEPHX2ACHESSTR4 | |
| SCHEMBL5459563 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4ETDP1P2RX7EPHX2 | |
| SCHEMBL4981612 | 0.76 | DRD4 (0.57) | P2RX7EPHX2DRD4SIGMAR1 | |
| SCHEMBL4981951 | 0.76 | MCHR1 (0.56) | ALDH1A1EPHX2SSTR4DRD4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064706-A1 | Piperidine Derivatives as Histamine H3 Receptor Ligands | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | US | disclosed |
| US-20080064706-A1 | Piperidine Derivatives as Histamine H3 Receptor Ligands | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | US | disclosed |
| US-20080064706-A1 | Piperidine Derivatives as Histamine H3 Receptor Ligands | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064706-A1 | Piperidine Derivatives as Histamine H3 Receptor Ligands | HRH3, HRH1, HRH4 | ALDH1A1 451/4885KDM4E 1044/4885TDP1 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.